C₁₄H₁₈ClNO₂

Base Information

• Chemical Name: C₁₄H₁₈ClNO₂
• CAS No.: 1281027-23-3
• Molecular Formula: C₁₄H₁₈ClNO₂
• Molecular Weight: 267.755
• Mol file: 1281027-23-3.mol

Synonyms:C₁₄H₁₈ClNO₂

Chemical Property of C₁₄H₁₈ClNO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₄H₁₈ClNO₂

There total 2 articles about C₁₄H₁₈ClNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

C14H16ClNO2 (1281027-14-2) → C14H18ClNO2 (1281027-23-3)

Guidance literature:

With sodium tetrahydroborate; potassium hydrogencarbonate; In ethanol; water; at 0 - 5 ℃;

DOI:10.1039/c0ob00559b

Reference yield:

4-(p-chlorophenyl)-1-butanol (19967-22-7) → C14H18ClNO2 (1281027-23-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / dichloromethane / 0 - 20 °C

2: sodium tetrahydroborate; potassium hydrogencarbonate / ethanol; water / 0 - 5 °C

With sodium tetrahydroborate; potassium hydrogencarbonate; triphenylphosphine; diethylazodicarboxylate; In ethanol; dichloromethane; water; 1: Mitsunobu reaction;

DOI:10.1039/c0ob00559b

upstream raw materials:

C₁₄H₁₆ClNO₂

4-(p-chlorophenyl)-1-butanol

Refernces