1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride

Base Information

• Chemical Name: 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride
• CAS No.: 117654-79-2
• Molecular Formula: C₂₄H₃₈N₄*4ClH
• Molecular Weight: 528.436
• Mol file: 117654-79-2.mol

Synonyms:1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride

Chemical Property of 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride

There total 2 articles about 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1,4-Diiodobutane (628-21-7) + N(1)-benzyl-N(1),N(3)-bis(2-nitrobenzenesulfonyl)propane-1,3-diamine (1111643-89-0) → 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride (117654-79-2)

Guidance literature:

DOI:10.1007/s00726-009-0429-2

Reference yield:

→ 1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride (117654-79-2)

Guidance literature:

Reference yield:

1,14-bis(phenylmethyl)-1,5,10,14-tetraazatetradecane tetrahydrochloride (117654-79-2) → N-(3-aminopropyl)-1,4-diaminobutane (124-20-9) + benzylamine (100-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1: recombinant human polyamine oxidase / pH 9.5 / Enzymatic reaction

2: spermine oxidase / pH 9.5 / Enzymatic reaction

With recombinant human polyamine oxidase; spermine oxidase;

DOI:10.1007/s00726-009-0429-2

upstream raw materials:

1,4-Diiodobutane

N⁽¹⁾-benzyl-N⁽¹⁾,N⁽³⁾-bis(2-nitrobenzenesulfonyl)propane-1,3-diamine

Downstream raw materials:

N-benzyl-1,3-diaminopropane

benzylamine

N-(3-aminopropyl)-1,4-diaminobutane

Spermine

Refernces

• 1、 -. "Polyamine derivatives as radioprotective agents". . . Retrieved 2008/06/13.