Methylpyridinium tosylate

Base Information

• Chemical Name: Methylpyridinium tosylate
• CAS No.: 38542-71-1
• Molecular Formula: C13H16NO3S+
• Molecular Weight: 265.333
• DSSTox Substance ID: DTXSID10959414
• NSC Number: 249267
• Mol file: 38542-71-1.mol

Synonyms:38542-71-1;methylpyridinium tosylate;n-methylpyridinium tosylate;SCHEMBL1982598;DTXSID10959414;OVFJVGPVSMMTSA-UHFFFAOYSA-M;NSC249267;NSC-249267;1-Methylpyridin-1-ium 4-methylbenzene-1-sulfonate

Chemical Property of Methylpyridinium tosylate

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 265.07726451
• Heavy Atom Count: 18
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)[O-].C[N+]1=CC=CC=C1

Technology Process of Methylpyridinium tosylate

There total 1 articles about Methylpyridinium tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

pyridine (110-86-1) + methyl p-toluene sulfonate (80-48-8) → N-methylpyridinium p-toluenesulfonate (38542-71-1)

Guidance literature:

In acetonitrile; for 24h; Inert atmosphere; Reflux;

DOI:10.1039/b906409e

Reference yield: 97.0%

N-methylpyridinium p-toluenesulfonate (38542-71-1) → N-methylpyridinium chloride (7680-73-1)

Guidance literature:

With Dowex 1-X₈ (Cl) 100-200 mesh standard grade resin; In water; Inert atmosphere;

DOI:10.1039/b906409e

Reference yield: 94.0%

N-methylpyridinium p-toluenesulfonate (38542-71-1) + 1,3,5-trimethyl-benzene (108-67-8) → 1,3,5-trimethyl-2-(toluene-4-sulfonyl)-benzene (5184-64-5)

Guidance literature:

N-methylpyridinium p-toluenesulfonate; With triphenylphosphine ditriflate; In dichloromethane; for 0.5h;

1,3,5-trimethyl-benzene; In dichloromethane; at 0 - 20 ℃; for 0.5h; chemoselective reaction;

DOI:10.1007/s13738-011-0062-3

upstream raw materials:

pyridine

methyl p-toluene sulfonate

Downstream raw materials:

N-methylpyridinium chloride

C₆H₈N⁽¹⁺⁾*C₇H₇O₃S^(1-)*C₃₆H₃₆O₆

2,4-dimethyl-1-[(4-methylphenyl)sulfonyl]benzene

bis(4-methylphenyl) sulfone

Refernces

• 1、 Gautam, Deepika,Gautam, Poonam,Chaudhary, Ram P.. "Substituted 4-thiazolidinones under solvent free conditions". . p. 147 - 150. Retrieved 2011.
• 2、 Khodaei,Nazari. "Sulfonylation of aromatic compounds with methyl p-toluenesulfonate as a sulfonylating precursor". . p. 507 - 512. Retrieved 2013/02/22.