Technology Process of 6-(4-Trifluoromethoxyphenyl)-nicotinic acid
There total 1 articles about 6-(4-Trifluoromethoxyphenyl)-nicotinic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
6-Chloronicotinic acid methyl ester; 4-trifluoromethoxyphenylboronic acid;
With
1,2-dimethoxyethane; sodium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane; water;
at 80 ℃;
for 16h;
With
water;
In
1,2-dimethoxyethane;
- Guidance literature:
-
methyl 6-[4-(trifluoromethoxy)phenyl]nicotinate;
With
potassium hydroxide;
In
methanol; water;
at 40 ℃;
With
hydrogenchloride; water;
pH=2;
With
diethyl ether;