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(S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid

Base Information Edit
  • Chemical Name:(S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid
  • CAS No.:1104077-73-7
  • Molecular Formula:C10H7F5O2
  • Molecular Weight:254.156
  • Hs Code.:
  • Mol file:1104077-73-7.mol
(S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid

Synonyms:(S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid

Suppliers and Price of (S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid
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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of (S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid Edit
Chemical Property:
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Technology Process of (S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid

There total 1 articles about (S)-3-(3,5-difluorophenyl)-4,4,4-trifluorobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With bis(norbornadiene)rhodium(l)tetrafluoroborate; (R)-1-{(Rp)-2-[2-(dicyclohexylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis(trifluoromethyl)phenyl]phosphine; hydrogen; In methanol; at 20 ℃; for 23h; under 2327.23 Torr; optical yield given as %ee;
DOI:10.1021/op900216v
Guidance literature:
With oxalyl dichloride; In N,N-dimethyl-formamide; toluene; at 20 ℃; for 1h;
Guidance literature:
With triethylamine; In tetrahydrofuran; at -70 - -5 ℃; for 2h;
upstream raw materials:

(E)-3-(3,5-difluorophenyl)-4,4,4-trifluorobut-2-enoic acid

Downstream raw materials:

C10H6ClF5O

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