C₁₄H₁₉NO₂

Base Information

• Chemical Name: C₁₄H₁₉NO₂
• CAS No.: 23784-78-3
• Molecular Formula: C₁₄H₁₉NO₂
• Molecular Weight: 233.31
• Mol file: 23784-78-3.mol

Synonyms:C₁₄H₁₉NO₂

Chemical Property of C₁₄H₁₉NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₉NO₂

There total 5 articles about C₁₄H₁₉NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-tert-Butylacrylamide (107-58-4,25267-41-8) + para-iodoanisole (696-62-8) → (2E)-N-(tert-butyl)-3-(4-methoxyphenyl)acrylamide (23784-78-3,780761-53-7)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1039/b918351p

Reference yield: 84.0%

N-tert-Butylacrylamide (107-58-4,25267-41-8) + 4-methoxyphenylboronic acid (5720-07-0) → (2E)-N-(tert-butyl)-3-(4-methoxyphenyl)acrylamide (23784-78-3,780761-53-7)

Guidance literature:

With tert-butyl-amphos chloride; sodium dodecyl-sulfate; sodium carbonate; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In toluene; at 20 ℃;

DOI:10.1055/s-2004-829161

Reference yield: 78.0%

C14H19NO (1052176-56-3) → 4-methoxy-trans-cinnamaldehyde (24680-50-0,71277-11-7,1963-36-6) + (2E)-N-(tert-butyl)-3-(4-methoxyphenyl)acrylamide (23784-78-3,780761-53-7)

Guidance literature:

With Oxone; aluminium trichloride; sodium hydrogencarbonate; In dichloromethane; at 20 ℃;

DOI:10.1080/00397910802138892

upstream raw materials:

N-tert-Butylacrylamide

4-methoxyphenylboronic acid

C₁₄H₁₉NO

para-iodoanisole

Refernces

• 1、 Sobjerg, Lina Sveidal,Gauthier, Delphine,Lindhardt, Anders Thyboe,Bunge, Michael,Finster, Kai,Meyer, Rikke Louise,Skrydstrup, Troels. "Bio-supported palladium nanoparticles as a catalyst for Suzuki-Miyaura and Mizoroki-Heck reactions". supporting information; experimental part. p. 2041 - 2046. Retrieved 2010/07/04.
• 2、 Lautens, Mark,Mancuso, John,Grover, Harpreet. "Rhodium-catalyzed heck-type coupling of boronic acids with activated alkenes in an aqueous emulsion". . p. 2006 - 2014. Retrieved 2007/10/03.