Technology Process of 2-<2-(3-ethoxycarbonyl-1-propyloxy)phenyl>benzofuran-6-carboxylic acid
There total 11 articles about 2-<2-(3-ethoxycarbonyl-1-propyloxy)phenyl>benzofuran-6-carboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene;
In
N,N-dimethyl acetamide; water;
for 2h;
Ambient temperature;
DOI:10.1248/cpb.47.226
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 34 percent / PdCl2(PPh3)2, Et3N / dimethylformamide / 110 °C
2: 45 percent / pyridinium chloride / 200 °C
3: 75 percent / NaH / dimethylformamide / Ambient temperature
4: 75 percent / NaClO2, NaH2PO4, 2-methyl-2-butene, DMA / H2O / Ambient temperature
With
bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; pyridine hydrochloride; 2,4-dichlorophenoxyacetic acid dimethylamine; sodium hydride; triethylamine;
In
water; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(98)00001-8
- Guidance literature:
-
Multi-step reaction with 7 steps
1: pyridine / CH2Cl2 / 0 °C
2: 74 percent / PdCl2(Ph3P)2, Et3N / dimethylformamide / 90 °C
3: 88 percent / K2CO3 / methanol / Ambient temperature
4: 34 percent / PdCl2(PPh3)2, Et3N / dimethylformamide / 110 °C
5: 45 percent / pyridinium chloride / 200 °C
6: 75 percent / NaH / dimethylformamide / Ambient temperature
7: 75 percent / NaClO2, NaH2PO4, 2-methyl-2-butene, DMA / H2O / Ambient temperature
With
pyridine; bis-triphenylphosphine-palladium(II) chloride; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; pyridine hydrochloride; 2,4-dichlorophenoxyacetic acid dimethylamine; sodium hydride; potassium carbonate; triethylamine;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(98)00001-8
