4-n-butanoyl-2-nitrochlorobenzene

Base Information

• Chemical Name: 4-n-butanoyl-2-nitrochlorobenzene
• CAS No.: 66353-38-6
• Molecular Formula: C₁₀H₁₀ClNO₃
• Molecular Weight: 227.647
• Mol file: 66353-38-6.mol

Synonyms:4-n-butanoyl-2-nitrochlorobenzene

Chemical Property of 4-n-butanoyl-2-nitrochlorobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-n-butanoyl-2-nitrochlorobenzene

There total 4 articles about 4-n-butanoyl-2-nitrochlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

4-n-butanoylchlorobenzene (4981-63-9) → 4-n-butanoyl-2-nitrochlorobenzene (66353-38-6)

Guidance literature:

With nitric acid; at -15 ℃;

DOI:10.1021/jm00364a004

Reference yield:

chlorobenzene (108-90-7) → 4-n-butanoyl-2-nitrochlorobenzene (66353-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / aluminium chloride / 4 h / 40 - 60 °C

2: 57 percent / HNO₃ / -15 °C

With aluminium trichloride; nitric acid;

DOI:10.1021/jm00364a004

Reference yield:

chlorobenzene (108-90-7) → 4-n-butanoyl-2-nitrochlorobenzene (66353-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminium chloride / 40 - 60 °C

2: HNO₃+H₂SO₄ / <-5

With aluminium trichloride; sulfuric acid; nitric acid;

upstream raw materials:

4-n-butanoylchlorobenzene

chlorobenzene

Downstream raw materials:

2-amino-4-n-butanoylchlorobenzene

1-(4-hydroxy-3-nitro-phenyl)-butan-1-one

4-chloro-3-nitrobenzoate

3,4-Diamino-butyrophenon

Refernces

• 1、 -. "Benzimidazole-2-carboxylic acid and derivatives thereof". . . Retrieved 2008/06/13.