eltrombopag methyl ester

Base Information

• Chemical Name: eltrombopag methyl ester
• CAS No.: 1246929-01-0
• Molecular Formula: C₂₆H₂₄N₄O₄
• Molecular Weight: 456.501
• Mol file: 1246929-01-0.mol

Synonyms:eltrombopag methyl ester

Chemical Property of eltrombopag methyl ester

Chemical Property:

• Boiling Point: 626.5±65.0 °C(Predicted)
• PKA: -1.27±0.40(Predicted)
• Density: 1.28±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

NLT 98% ^*data from raw suppliers

EltrombopagMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Eltrombopag Methyl Ester, is a metabolite of Eltrombopag (E508000), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

Technology Process of eltrombopag methyl ester

There total 1 articles about eltrombopag methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.3%

methanol (67-56-1) + Eltrombopag → eltrombopag methyl ester (1246929-01-0)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; Reflux;

upstream raw materials:

methanol

Refernces