2-deoxy-α-D-ribose-1-phosphate

Base Information

• Chemical Name: 2-deoxy-α-D-ribose-1-phosphate
• CAS No.: 18684-29-2
• Molecular Formula: C₅H₁₁O₇P
• Molecular Weight: 214.112
• Mol file: 18684-29-2.mol

Synonyms:2-deoxy-α-D-ribose-1-phosphate

Chemical Property of 2-deoxy-α-D-ribose-1-phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-deoxy-α-D-ribose-1-phosphate

There total 8 articles about 2-deoxy-α-D-ribose-1-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Iodo-2'-deoxyuridine (54-42-2,162239-35-2) → 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3) + 5-iodouracil (696-07-1)

Guidance literature:

With recombinant thymidine phosphorylase from Mycoplasma hyorhinis; at 37 ℃; for 0.333333h; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1042/BJ20112225

Reference yield:

5-Fluoro-2'-deoxyuridine (50-91-9) → 5-fluorouracil (51-21-8) + 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3)

Guidance literature:

With recombinant thymidine phosphorylase from Mycoplasma hyorhinis; at 37 ℃; for 0.333333h; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1042/BJ20112225

Reference yield:

uridine (58-96-8) → 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3) + uracil (66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6)

Guidance literature:

With human uridine phosphorylase (UP); In water; at 20 ℃; Conversion of starting material; Enzymatic reaction; Aqueous phosphate buffer;

upstream raw materials:

thymidine

5-Fluoro-2'-deoxyuridine

uridine

5-Iodo-2'-deoxyuridine

Refernces

• 1、 -. "PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2 ' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER". Page/Page column 66-67. . Retrieved 2012/09/21.
• 2、 Secrist III, John A.. "Gene therapy of cancer: activation of nucleoside prodrugs with e. colipurine nucleoside phosphorylase". . p. 745 - 757. Retrieved 2007/10/03.