5,6-Quinoxalinediamine, N6-methyl-

Base Information

• Chemical Name: 5,6-Quinoxalinediamine, N6-methyl-
• CAS No.: 888037-23-8
• Molecular Formula: C₉H₁₀N₄
• Molecular Weight: 174.205
• Mol file: 888037-23-8.mol

Synonyms:5-Amino-6-methylaminoquinoxaline

Chemical Property of 5,6-Quinoxalinediamine, N6-methyl-

Chemical Property:

• PSA: 63.83000
• LogP: 1.90790

Purity/Quality:

5-Amino-6-methylaminoquinoxaline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-Quinoxalinediamine, N6-methyl-

There total 6 articles about 5,6-Quinoxalinediamine, N6-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-methylamino-5-nitroquinoxaline → N6-methylquinoxaline-5,6-diamine (888037-23-8)

Guidance literature:

With hydrazine hydrate; Raney Ni; In methanol; at 20 ℃; for 1h;

Reference yield:

N-6-quinoxalinylacetamide (26556-22-9) → N6-methylquinoxaline-5,6-diamine (888037-23-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / water; tetrahydrofuran; mineral oil / 0.17 h / 20 °C

1.2: 2 h / 20 °C

2.1: potassium nitrate; sulfuric acid / dichloromethane / 4 h / 0 - 20 °C

2.2: pH ~ 9

3.1: hydrazine hydrate / Raney Ni / methanol / 1 h / 20 °C

With sulfuric acid; sodium hydride; hydrazine hydrate; potassium nitrate; Raney Ni; In tetrahydrofuran; methanol; dichloromethane; water; mineral oil;

Reference yield:

N-methyl-N-(quinoxalin-6-yl)acetamide (1384863-11-9) → N6-methylquinoxaline-5,6-diamine (888037-23-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium nitrate; sulfuric acid / dichloromethane / 4 h / 0 - 20 °C

1.2: pH ~ 9

2.1: hydrazine hydrate / Raney Ni / methanol / 1 h / 20 °C

With sulfuric acid; hydrazine hydrate; potassium nitrate; Raney Ni; In methanol; dichloromethane;

upstream raw materials:

N-6-quinoxalinylacetamide

N-methyl-N-(quinoxalin-6-yl)acetamide

6-nitroquinoxaline

4-Nitrophenylene-1,2-diamine

Refernces