DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID

Base Information

• Chemical Name: DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID
• CAS No.: 20263-06-3
• Molecular Formula: C₃H₈NO₅P
• Molecular Weight: 169.074
• Hs Code.: 29310099
• Mol file: 20263-06-3.mol

Synonyms:3-Phosphono-DL-alanine;

Chemical Property of DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID

Chemical Property:

• Appearance/Colour: white to almost white powder
• Vapor Pressure: 1.34E-10mmHg at 25°C
• Melting Point: 227-229 °C(lit.)
• Refractive Index: 1.558
• Boiling Point: 481.6 °C at 760 mmHg
• Flash Point: 245.1 °C
• PSA: 130.66000
• Density: 1.763 g/cm³
• LogP: -0.72370
• Storage Temp.: 0-6°C
• Solubility.: Water (Slightly, Heated)

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-AP3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: DL-2-Amino-3-phosphonopropionic acid (AP3) is an inhibitor of phosphoserine phosphatase and mGluR. Also known as the antagonist of a receptor that is coupled to phosphoinositide metabolism in brain slices. D,L-2-Amino-3-phosphonopropionic acid is also an inhibitor of metabotropic glutamate receptors in rat brain.

Technology Process of DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID

There total 2 articles about DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-((S)-1-Phenyl-ethylamino)-3-phosphono-propionic acid (86554-28-1,86554-34-9) → 2-Amino-3-phosphono-propionic acid (5652-28-8,20263-06-3,23052-80-4,128241-72-5) + 2-Amino-3-phosphono-propionic acid (5652-28-8,20263-06-3,23052-80-4,128241-72-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; at 100 ℃; for 10h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(01)91895-2

Reference yield:

2-((S)-1-Phenyl-ethylamino)-3-phosphono-propionic acid (86554-28-1,86554-34-9) → 2-Amino-3-phosphono-propionic acid (5652-28-8,20263-06-3,23052-80-4,128241-72-5) + 2-Amino-3-phosphono-propionic acid (5652-28-8,20263-06-3,23052-80-4,128241-72-5)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; at 100 ℃; for 10h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(01)91895-2

upstream raw materials:

2-((S)-1-Phenyl-ethylamino)-3-phosphono-propionic acid

Refernces