spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate

Base Information

• Chemical Name: spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate
• CAS No.: 76583-95-4
• Molecular Formula: C₇H₇O₃S*C₁₉H₂₂NS
• Molecular Weight: 467.653
• Mol file: 76583-95-4.mol

Synonyms:spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate

Chemical Property of spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate

There total 9 articles about spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-(hydroxymethyl)-2'-(piperidinomethyl)diphenyl sulfide (64465-86-7) + p-toluenesulfonyl chloride (98-59-9) → spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate (76583-95-4)

Guidance literature:

With triethylamine; In acetonitrile; for 18h; Ambient temperature;

DOI:10.1021/jo00321a020

Reference yield:

2-carbethoxy-2'-(piperidinocarbonyl)diphenyl sulfide (62220-63-7) → spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate (76583-95-4)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄

2: 45 percent / triethylamine / acetonitrile / 18 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In acetonitrile;

DOI:10.1021/jo00321a020

Reference yield:

2-carbethoxy-2'-chlorocarbonyldiphenyl sulfide (62220-53-5) → spiro<5H,7H-dibenzo<1,5>thiazocinepentamethyleneammonium> tosylate (76583-95-4)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / acetonitrile / 3 h / Ambient temperature

2: LiAlH₄

3: 45 percent / triethylamine / acetonitrile / 18 h / Ambient temperature

With lithium aluminium tetrahydride; triethylamine; In acetonitrile;

DOI:10.1021/jo00321a020

upstream raw materials:

2-(hydroxymethyl)-2'-(piperidinomethyl)diphenyl sulfide

p-toluenesulfonyl chloride

2-carbethoxy-2'-(piperidinocarbonyl)diphenyl sulfide

2-carbethoxy-2'-chlorocarbonyldiphenyl sulfide

Refernces