C₉H₁₀ClN₃OS

Base Information

• Chemical Name: C₉H₁₀ClN₃OS
• CAS No.: 29527-10-4
• Molecular Formula: C₉H₁₀ClN₃OS
• Molecular Weight: 243.717
• Mol file: 29527-10-4.mol

Synonyms:C₉H₁₀ClN₃OS

Chemical Property of C₉H₁₀ClN₃OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₉H₁₀ClN₃OS

There total 2 articles about C₉H₁₀ClN₃OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-chlorobenzoic acid hydrazide (536-40-3) + methyl thioisocyanate (556-61-6) → C9H10ClN3OS (29527-10-4)

Guidance literature:

In tetrahydrofuran; for 2h; Heating;

Reference yield:

→ C9H10ClN3OS (29527-10-4)

Guidance literature:

entspr. Benzhydrazid, Isothiocyanat;

DOI:10.1021/jm00298a021

Reference yield: 31.0%

C9H10ClN3OS (29527-10-4) → 5-(4-Chloro-phenyl)-4-methyl-2,4-dihydro-[1,2,4]triazole-3-thione (29527-27-3)

Guidance literature:

With sodium hydrogencarbonate; for 24h; Heating;

upstream raw materials:

4-chlorobenzoic acid hydrazide

methyl thioisocyanate

Downstream raw materials:

5-(4-Chloro-phenyl)-4-methyl-2,4-dihydro-[1,2,4]triazole-3-thione

3-(4-chloro-phenyl)-4-methyl-5-methylsulfanyl-4H-[1,2,4]triazole

Refernces

• 1、 Geng, Yun-He,Wei, Zeng-Quan,Xu, Zhi,Na, Lu-Xin,Zhang, Shu,Guo, Hui-Yuan,Liu, Ming-Liang,Feng, Lian-Shun,You, Xue-Fu. "Design, synthesis and antibacterial evaluation of 1-[(1R,2S)-2-Fluorocyclopropyl] Ciprofloxacin-(4-Methyl-3-Aryl)-1,2,4-Triazole-5(4H)-Thione Hybrids". . p. 101 - 107. Retrieved 2019/08/01.
• 2、 Kane,Staeger,Dalton,Miller,Dudley,Ogden,Kehne,Ketteler,McCloskey,Senyah,Chmielewski,Miller. "5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents". . p. 125 - 132. Retrieved 2007/10/02.