5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon

Base Information

• Chemical Name: 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon
• CAS No.: 74995-97-4
• Molecular Formula: C₁₆H₁₈O₅
• Molecular Weight: 290.316
• Mol file: 74995-97-4.mol

Synonyms:5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon

Chemical Property of 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon

There total 3 articles about 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

protogenkwanin (74996-29-5) → 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon (74995-97-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0040-4020(01)92024-1

Reference yield:

protogenkwanin-4'-glucoside (78983-46-7) → 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon (74995-97-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / cellulase from Aspergillus niger, O_.1M acetate buffer / 144 h / 40 °C / pH=4.6

2: 22 percent / H₂ / 10percent palladised charcoal / ethanol

With cellulase from Aspergillus niger; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0040-4020(01)92024-1

Reference yield:

protogenkwanin 4'-glucoside → 5-hydroxy-2-(4-hydroxycyclohexyl)-7-methoxy-4-chromenon (74995-97-4)

Guidance literature:

Multi-step reaction with 2 steps

1: β-D-glucosidase (sweet almond emulsin)

2: H₂ / Pd/C / ethanol / Ambient temperature

With β-D-glucosidase (sweet almond emulsin); hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/S0040-4039(00)71378-5

upstream raw materials:

protogenkwanin

protogenkwanin-4'-glucoside

Refernces

• 1、 Hauteville,Chopin,Gieger,Schuler. "Protogenkwanin 4'-glucoside, a new type of natural flavonoid with a non aromatic B-ring". . p. 1227 - 1230. Retrieved 2007/10/02.