cytidine 2′,3′-cyclic monophosphate

Base Information

• Chemical Name: cytidine 2′,3′-cyclic monophosphate
• CAS No.: 50574-59-9
• Molecular Formula: C₉H₁₁N₃O₇P
• Molecular Weight: 304.176
• Mol file: 50574-59-9.mol

Synonyms:cytidine 2′,3′-cyclic monophosphate

Chemical Property of cytidine 2′,3′-cyclic monophosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cytidine 2′,3′-cyclic monophosphate

There total 5 articles about cytidine 2′,3′-cyclic monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2-thiocytidine (13233-20-0,13239-97-9) → 2,4-diaminopyrimidine (156-81-0) + cytidine 2′,3′-cyclic monophosphate (50574-59-9) + CYTIDINE (65-46-3)

Guidance literature:

With dihydrogen phosphate; formamide; Heating;

DOI:10.1038/nchem.2664

Reference yield:

cytidyl-3',5'-adenosine → cytidine 2′,3′-cyclic monophosphate (50574-59-9) + adenosine (58-61-7)

Guidance literature:

With 5-(N-guanidinomethyl)-17-(N-[1,4,7-triazacyclonon-1-yl]methyl)-25,26,27,28-tetrakis(2-ethoxyethoxy)calix[4]arene Tetrahydrochloride; copper dichloride; In dimethyl sulfoxide; at 50 ℃; pH=8.8; Kinetics;

DOI:10.1021/acs.joc.5b00965

Reference yield:

2,2'-anhydroribocytidine → cytidine 2′,3′-cyclic monophosphate (50574-59-9) + CYTIDINE (65-46-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrosulfide anion; water / formamide

2: water / 60 h / UV-irradiation

3: formamide; dihydrogen phosphate / Heating

With water; hydrosulfide anion; dihydrogen phosphate; formamide; In formamide;

DOI:10.1038/nchem.2664

upstream raw materials:

2-thiocytidine

Downstream raw materials:

3'-monophosphate of cytidine

CYTIDINE

Refernces

• 1、 Chen, Jack L.-Y.,Pezzato, Cristian,Scrimin, Paolo,Prins, Leonard J.. "Chiral Nanozymes-Gold Nanoparticle-Based Transphosphorylation Catalysts Capable of Enantiomeric Discrimination". supporting information. p. 7028 - 7032. Retrieved 2016/05/19.
• 2、 Salvio, Riccardo,Cacciapaglia, Roberta,Mandolini, Luigi,Sansone, Francesco,Casnati, Alessandro. "Diguanidinocalix[4]arenes as effective and selective catalysts of the cleavage of diribonucleoside monophosphates". . p. 34412 - 34416. Retrieved 2014/11/12.