4-(trifluoromethyl)benzenesulfinyl chloride

Base Information

• Chemical Name: 4-(trifluoromethyl)benzenesulfinyl chloride
• CAS No.: 50986-84-0
• Molecular Formula: C₇H₄ClF₃OS
• Molecular Weight: 228.622
• Mol file: 50986-84-0.mol

Synonyms:4-(trifluoromethyl)benzenesulfinyl chloride

Chemical Property of 4-(trifluoromethyl)benzenesulfinyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(trifluoromethyl)benzenesulfinyl chloride

There total 4 articles about 4-(trifluoromethyl)benzenesulfinyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-trifluoromethylphenyl disulfide (18715-45-2) → 4-(trifluoromethyl)benzenesulfinyl chloride (50986-84-0)

Guidance literature:

With sulfuryl dichloride; acetic acid; at -20 ℃; for 3.5h;

DOI:10.1002/anie.201603576

Reference yield:

4-trifluoromethylbenzenethiol (825-83-2) → 4-(trifluoromethyl)benzenesulfinyl chloride (50986-84-0)

Guidance literature:

With sulfuryl dichloride; acetic acid; at -20 - 20 ℃; Inert atmosphere;

DOI:10.1002/chem.201001749

Reference yield:

lithium 4-(trifluoromethyl)benzenesulfinate → 4-(trifluoromethyl)benzenesulfinyl chloride (50986-84-0)

Guidance literature:

With sulfuryl dichloride; In dichloromethane; for 2h;

DOI:10.1002/(SICI)1099-0690(199905)1999:5<1011::AID-EJOC1011>3.0.CO;2-H

upstream raw materials:

p-trifluoromethylphenyl bromide

4-trifluoromethylbenzenethiol

4-trifluoromethylphenyl disulfide

Downstream raw materials:

4-(trifluoromethyl)benzenesulfinic acid

C₁₄H₉Cl₂F₃N₂O₂S

C₁₄H₁₀ClF₃N₂O₂S

C₁₉H₃₂F₃NO₂SSi

Refernces

• 1、 Ammann, Stephen E.,Liu, Wei,White, M. Christina. "Enantioselective Allylic C?H Oxidation of Terminal Olefins to Isochromans by Palladium(II)/Chiral Sulfoxide Catalysis". . p. 9571 - 9575. Retrieved 2016/08/10.
• 2、 Reggelin, Michael,Gerlach, Matthias,Vogt, Melanie. "Metallated 2-alkenyl sulfoximines in asymmetric synthesis: Regio- and stereoselective synthesis of highly substituted oxabicyclic ethers and studies towards the total syntheses of the euglobals G1 and G2 and arenaran A". . p. 1011 - 1031. Retrieved 2007/10/03.