C₁₅H₂₀FN₃O₂S

Base Information

• Chemical Name: C₁₅H₂₀FN₃O₂S
• CAS No.: 1374820-47-9
• Molecular Formula: C₁₅H₂₀FN₃O₂S
• Molecular Weight: 325.407
• Mol file: 1374820-47-9.mol

Synonyms:C₁₅H₂₀FN₃O₂S

Chemical Property of C₁₅H₂₀FN₃O₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₂₀FN₃O₂S

There total 1 articles about C₁₅H₂₀FN₃O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-6-fluoro-1,3-benzothiazole (348-40-3) → C15H20FN3O2S (1374820-47-9)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrochloride; hydrazine hydrate / ethylene glycol / 2 h / 140 °C

2: thionyl chloride / 2 h / 50 °C

3: potassium carbonate / N,N-dimethyl-formamide / 2 h / 120 °C

With thionyl chloride; hydrazine hydrochloride; potassium carbonate; hydrazine hydrate; In ethylene glycol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.03.079

Reference yield:

C15H20FN3O2S (1374820-47-9) → C17H14Cl2FN3S

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere

2.1: sodium methylate / methanol / 0.17 h / 20 °C / pH 12

2.2: 1 h / 50 °C

With sodium methylate; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1016/j.bmcl.2012.03.079

Reference yield:

C15H20FN3O2S (1374820-47-9) → C17H16Cl2FN3S (1374820-29-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere

2.1: sodium methylate / methanol / 0.17 h / 20 °C / pH 12

2.2: 1 h / 50 °C

3.1: sodium cyanoborohydride / methanol / 6 h / 50 °C

With sodium methylate; sodium cyanoborohydride; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1016/j.bmcl.2012.03.079

upstream raw materials:

2-amino-6-fluoro-1,3-benzothiazole

Downstream raw materials:

C₁₇H₁₆Cl₂FN₃S

Refernces