2-hydroxy-1,12-dicarba-closo-dodecaborane

Base Information

• Chemical Name: 2-hydroxy-1,12-dicarba-closo-dodecaborane
• CAS No.: 31726-41-7
• Molecular Formula: C₂H₁₂B₁₀O
• Molecular Weight: 160.227
• Mol file: 31726-41-7.mol

Synonyms:2-hydroxy-1,12-dicarba-closo-dodecaborane

Chemical Property of 2-hydroxy-1,12-dicarba-closo-dodecaborane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-hydroxy-1,12-dicarba-closo-dodecaborane

There total 4 articles about 2-hydroxy-1,12-dicarba-closo-dodecaborane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2-iodo-closo-1,12-dodecaborane (22784-33-4) + aniline (62-53-3) → 2-hydroxy-1,12-dicarba-closo-dodecaborane (31726-41-7) + N-(1,12-dicarba-closo-dodecaboran-2-yl)benzenamine (936951-92-7)

Guidance literature:

With t-BuONa; Pd(dba)2; BINAP; In 1,4-dioxane; under Ar atm. 2-iodo-p-carborane, aniline, t-BuONa, Pd(dba)2 and BINAP in dioxane were heated at 100°C; react. mixt. was diluted with Et2O, filtered through silica, flash chromy.; elem. anal.;

DOI:10.1021/om0611756

Reference yield: 47.0%

2-iodo-closo-1,12-dodecaborane (22784-33-4) + 4-methoxy-aniline (104-94-9) → 2-hydroxy-1,12-dicarba-closo-dodecaborane (31726-41-7) + N-(1,12-dicarba-closo-dodecaboran-2-yl)-4-methoxybenzenamine (936951-94-9)

Guidance literature:

With t-BuONa; Pd(dba)2; BINAP; In 1,4-dioxane; under Ar atm. 2-iodo-p-carborane, aniline, t-BuONa, Pd(dba)2 and BINAP in dioxane were heated at 100°C; react. mixt. was diluted with Et2O, filtered through silica, flash chromy.; elem. anal.;

DOI:10.1021/om0611756

Reference yield: 33.0%

morpholine (110-91-8,99108-56-2) + 2-iodo-closo-1,12-dodecaborane (22784-33-4) → 1,12-dicarbora-closo-dodecaborane (20644-12-6) + 2-hydroxy-1,12-dicarba-closo-dodecaborane (31726-41-7) + N-(1,12-dicarba-closo-dodecaboran-2-yl)morpholine (936951-95-0)

Guidance literature:

With t-BuONa; Pd(dba)2; PBu(t)3*HBF₄; In 1,4-dioxane; under Ar atm. 2-iodo-p-carborane, carbazole, t-BuONa, Pd(dba)2 and PBu(t)3*HBF4 in dioxane were heated at 100°C for 48 h; react. mixt. was diluted with Et2O, filtered through silica, flash chromy.; elem. anal.;

DOI:10.1021/om0611756

upstream raw materials:

morpholine

2-iodo-closo-1,12-dodecaborane

aniline

4-methoxy-aniline

Refernces