15-Hexadecenoic acid, 14-hydroxy-15-methyl-

Base Information

• Chemical Name: 15-Hexadecenoic acid, 14-hydroxy-15-methyl-
• CAS No.: 89328-43-8
• Molecular Formula: C₁₇H₃₂O₃
• Molecular Weight: 284.439
• Mol file: 89328-43-8.mol

Synonyms:15-Hexadecenoic acid, 14-hydroxy-15-methyl-

Chemical Property of 15-Hexadecenoic acid, 14-hydroxy-15-methyl-

Chemical Property:

• PSA: 57.53000
• LogP: 4.68920

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 15-Hexadecenoic acid, 14-hydroxy-15-methyl-

There total 3 articles about 15-Hexadecenoic acid, 14-hydroxy-15-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

methyl 14-hydroxy-15-methyl-15-hexadecenoate (89328-42-7) → 14-hydroxy-15-methyl-15-hexadecenoic acid (89328-43-8)

Guidance literature:

With potassium hydroxide; In methanol; water; for 1.5h; Heating;

DOI:10.1002/hlca.19830660827

Reference yield:

methyl 13-(chloroformyl)tridecanoate (50516-00-2) → 14-hydroxy-15-methyl-15-hexadecenoic acid (89328-43-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / H₂, 2,6-lutidine / 10 percent Pd/C / tetrahydrofuran / 3 h / Ambient temperature

2: 72.2 percent / tetrahydrofuran / 4 h / Ambient temperature

3: 79.1 percent / 2 N KOH / H₂O; methanol / 1.5 h / Heating

With 2,6-dimethylpyridine; potassium hydroxide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; water;

DOI:10.1002/hlca.19830660827

Reference yield:

methyl 13-formyltridecanoate (70219-57-7) → 14-hydroxy-15-methyl-15-hexadecenoic acid (89328-43-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 72.2 percent / tetrahydrofuran / 4 h / Ambient temperature

2: 79.1 percent / 2 N KOH / H₂O; methanol / 1.5 h / Heating

With potassium hydroxide; In tetrahydrofuran; methanol; water;

DOI:10.1002/hlca.19830660827

upstream raw materials:

methyl 14-hydroxy-15-methyl-15-hexadecenoate

methyl 13-formyltridecanoate

methyl 13-(chloroformyl)tridecanoate

Refernces