C₁₅H₁₉NO₂S

Base Information

• Chemical Name: C₁₅H₁₉NO₂S
• CAS No.: 1015076-74-0
• Molecular Formula: C₁₅H₁₉NO₂S
• Molecular Weight: 277.387
• Mol file: 1015076-74-0.mol

Synonyms:C₁₅H₁₉NO₂S

Chemical Property of C₁₅H₁₉NO₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₅H₁₉NO₂S

There total 3 articles about C₁₅H₁₉NO₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C14H19NO4S (1015076-73-9) + tiolacetic acid (507-09-5) → C15H19NO2S (1015076-74-0)

Guidance literature:

With caesium carbonate; In methanol; N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

C13H17NO2 (1015076-72-8) → C15H19NO2S (1015076-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3.25 h / 0 °C

2: caesium carbonate / methanol; N,N-dimethyl-formamide / 20 °C

With caesium carbonate; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

C14H17NO3 (1015076-70-6) → C15H19NO2S (1015076-74-0)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran; tert-butyl alcohol / 0 - 50 °C

2: triethylamine / dichloromethane / 3.25 h / 0 °C

3: caesium carbonate / methanol; N,N-dimethyl-formamide / 20 °C

With lithium aluminium tetrahydride; caesium carbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol;

upstream raw materials:

C₁₄H₁₉NO₄S

tiolacetic acid

C₁₃H₁₇NO₂

C₁₄H₁₇NO₃

Downstream raw materials:

1-(sulfanylmethyl)cyclopropaneacetic acid

Refernces