2-acetyl-5-(benzyloxy)phenyl acetate

Base Information

• Chemical Name: 2-acetyl-5-(benzyloxy)phenyl acetate
• CAS No.: 56133-02-9
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.312
• Mol file: 56133-02-9.mol

Synonyms:2-acetyl-5-(benzyloxy)phenyl acetate

Chemical Property of 2-acetyl-5-(benzyloxy)phenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetyl-5-(benzyloxy)phenyl acetate

There total 3 articles about 2-acetyl-5-(benzyloxy)phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

Acetyl bromide (506-96-7) + 2,4-bis(benzyloxy)acetophenone (22877-01-6) → 1-[4-(benzyloxy)-2-hydroxyphenyl]ethanone (29682-12-0) + 2-acetyl-5-(benzyloxy)phenyl acetate (56133-02-9)

Guidance literature:

With lithium bromide; In dichloromethane; at 30 - 35 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jo801659g

Reference yield:

acetic acid 4-acetyl-3-hydroxyphenyl ester (42059-48-3) + benzyl chloride (100-44-7) → 2-acetyl-5-(benzyloxy)phenyl acetate (56133-02-9)

Guidance literature:

With potassium carbonate; acetone; potassium iodide;

DOI:10.1021/ja01553a053

Reference yield:

→ 2-acetyl-5-(benzyloxy)phenyl acetate (56133-02-9)

Guidance literature:

aus II mit Benzylchlorid;

upstream raw materials:

acetic acid 4-acetyl-3-hydroxyphenyl ester

benzyl chloride

Acetyl bromide

2,4-bis(benzyloxy)acetophenone

Downstream raw materials:

1-[4-(benzyloxy)-2-hydroxyphenyl]ethanone

Refernces

• 1、 Tiwari,Sharma. "Synthesis of possible antifertility compounds: PartI. Synthesis of 4 o benzyl 2 hydroxy phenyl N arylthiosemicarbazones". . p. 153 - 154. Retrieved 2007/10/10.