allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate

Base Information

• Chemical Name: allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate
• CAS No.: 1367074-91-6
• Molecular Formula: C₁₉H₁₉NO₄
• Molecular Weight: 325.364
• Mol file: 1367074-91-6.mol

Synonyms:allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate

Chemical Property of allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate

There total 2 articles about allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl 2-(3-methoxyphenyl)-2-oxoacetate (1367075-18-0) + 4-methoxy-aniline (104-94-9) → allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate (1367074-91-6)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 22h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2012.01.133

Reference yield:

diallyl oxalate (615-99-6) → allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate (1367074-91-6)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; diethyl ether / 2 h / -80 °C / Inert atmosphere

2: toluene-4-sulfonic acid / benzene / 22 h / Inert atmosphere; Reflux

With toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; benzene;

DOI:10.1016/j.tetlet.2012.01.133

Reference yield: 85.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + C18H15(2)H2NO3 (1367075-11-3) + allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate (1367074-91-6) + ethylaluminum dichloride (563-43-9) + diethylaluminium chloride (96-10-6) → C21H23(2)H2NO3 (1367075-12-4) + methyl 2-[N-ethyl-N-(4-methoxyphenyl)amino]-2-(3-methoxyphenyl)pent-4-enoate (1367074-99-4)

Guidance literature:

C₁₈H₁₅⁽²⁾H₂NO₃; allyl 2-(4-methoxyphenylimino)-2-(3-methoxyphenyl)acetate; ethylaluminum dichloride; diethylaluminium chloride; In 1,2-dimethoxyethane; hexane; at 40 ℃; for 6.5h; Inert atmosphere;

With water; Rochelle's salt; In 1,2-dimethoxyethane; hexane; at 20 ℃; for 0.5h;

diazomethane; In diethyl ether; at 0 ℃; for 0.166667h;

DOI:10.1016/j.tetlet.2012.01.133

upstream raw materials:

allyl 2-(3-methoxyphenyl)-2-oxoacetate

4-methoxy-aniline

diallyl oxalate

Downstream raw materials:

C₂₁H₂₃⁽²⁾H₂NO₃

methyl 2-[N-ethyl-N-(4-methoxyphenyl)amino]-2-(3-methoxyphenyl)pent-4-enoate

methyl 2-[N-isobutyl-N-(4-methoxyphenyl)amino]-2-(3-methoxyphenyl)pent-4-enoate

Refernces