C₁₅H₁₅ClN₂O₃S

Base Information

• Chemical Name: C₁₅H₁₅ClN₂O₃S
• CAS No.: 1398574-80-5
• Molecular Formula: C₁₅H₁₅ClN₂O₃S
• Molecular Weight: 338.815
• Mol file: 1398574-80-5.mol

Synonyms:C₁₅H₁₅ClN₂O₃S

Chemical Property of C₁₅H₁₅ClN₂O₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₅ClN₂O₃S

There total 3 articles about C₁₅H₁₅ClN₂O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl hydrogen succinate (3878-55-5) + 2-amino-4-(4’-chlorophenyl)-5-methyl-1,3-thiazole (82632-77-7) → C15H15ClN2O3S (1398574-80-5)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; for 24h;

DOI:10.1016/j.ejmech.2012.03.006

Reference yield:

4'-chloropropiophenone (6285-05-8) → C15H15ClN2O3S (1398574-80-5)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(ll) bromide / ethanol; chloroform; ethyl acetate / 0.5 h / 65 °C

2: ethanol / 2 h / Reflux

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 24 h

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; copper(ll) bromide; In ethanol; chloroform; ethyl acetate;

DOI:10.1016/j.ejmech.2012.03.006

Reference yield:

2-bromo-1-(4-chlorophenyl)-1-propanone (877-37-2) → C15H15ClN2O3S (1398574-80-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 2 h / Reflux

2: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / chloroform / 24 h

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; chloroform;

DOI:10.1016/j.ejmech.2012.03.006

upstream raw materials:

4'-chloropropiophenone

methyl hydrogen succinate

2-amino-4-(4’-chlorophenyl)-5-methyl-1,3-thiazole

2-bromo-1-(4-chlorophenyl)-1-propanone

Downstream raw materials:

4-((4-(4-chlorophenyl)-5-methylthiazol-2-yl)amino)-4-oxobutanoic acid

Refernces