2C-C

Base Information

• Chemical Name: 2C-C
• CAS No.: 88441-15-0
• Molecular Formula: C10H15Cl2NO2
• Molecular Weight: 252.14
• Hs Code.: 2922299090
• Mol file: 88441-15-0.mol

Synonyms:Benzeneethanamine,4-chloro-2,5-dimethoxy-, hydrochloride (9CI);4-Chloro-2,5-dimethoxyphenethylaminehydrochloride;

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 2C-C

Chemical Property:

• Melting Point: 213-216°C
• Flash Point: 9℃
• PSA: 44.48000
• LogP: 3.36070
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere

Purity/Quality:

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45

MSDS Files:

SDS file from LookChem

Useful:

• Description: A series of 2,5-dimethoxy phenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are substituted at the 4 position of the aromatic ring. Many are scheduled as illegal substances. 2C-C is described formally as 2,5-dimethoxy-4-chlorophenethylamine. A known hallucinogen, this compound stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50 = 31 and 63 μM, respectively). LC-MS/MS screening methods for this designer drug have been developed. This product is intended for forensic and research purposes. A series of 2,5-dimethoxyphenethylamines, collectively referred to as 2Cs, have psychoactive effects. The most effective 2C compounds are substituted at the four position of the aromatic ring. Many are scheduled as illegal substances. 2C-C is described formally as 2,5-dimethoxy-4-chlorophenethylamine. A known hallucinogen, this compound stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50s = 31 and 63 μM, respectively). LC-MS/MS screening methods for this designer drug have been developed. This product is intended for forensic and research purposes.
• Uses: A phenethylamine derivative; 2C-series designer drugs.

Technology Process of 2C-C

There total 1 articles about 2C-C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethoxyphenethylamine (3600-86-0) → 1-(2,5-dimethoxy-4-chlorophenyl)-2-aminoethane hydrochloride (88441-15-0)

Guidance literature:

With sulfuryl dichloride; acetic acid; at 20 ℃; for 3h;

DOI:10.1002/jlcr.1139

Reference yield:

C8H7(18)FO2 (136507-16-9) + 1-(2,5-dimethoxy-4-chlorophenyl)-2-aminoethane hydrochloride (88441-15-0) → C18H21Cl(18)FNO3

Guidance literature:

With sodium cyanoborohydride; acetic acid; In dimethyl sulfoxide; at 130 ℃; for 0.166667h;

DOI:10.1016/j.bmc.2016.08.056

Reference yield:

1-(2,5-dimethoxy-4-chlorophenyl)-2-aminoethane hydrochloride (88441-15-0) + ortho-anisaldehyde (135-02-4) → C18H20ClNO3

Guidance literature:

With triethylamine; In ethanol; at 20 ℃;

DOI:10.1021/cn400216u

upstream raw materials:

2,5-dimethoxyphenethylamine

Downstream raw materials:

2-(((4-chloro-2,5-dimethoxyphenethyl)amino)methyl)phenol

C₁₇H₁₉ClFNO₂

C₁₈H₂₀ClNO₄

Refernces