Technology Process of (+/-)-3-Hydroxy-4-oxo-β-jonon
There total 8 articles about (+/-)-3-Hydroxy-4-oxo-β-jonon which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-trimethylsilyloxy-β-ionone 9-ethylene ketal;
With
peracetic acid;
In
acetic acid; toluene;
at -15 - -10 ℃;
for 2 - 4h;
With
hydrogenchloride;
In
water; acetic acid; toluene;
for 1.5h;
With
sodium hydroxide;
In
water; acetic acid; toluene;
pH=7;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 52 percent / pyridinium chlorochromate / dimethylsulfoxide / 5 h / 105 °C
2: 52 percent / triethyl orthoformate, p-toluenesulfonic acid / 0.5 h / oxo-β-ionone:ethylene glycol:triethyl orthoformate=1:1.5:1.2
3: toluene / 8 h / Heating
4: 1N HCl / methanol / 3 h
5: 85 percent / 1N NaOH / methanol / 0.5 h
With
hydrogenchloride; sodium hydroxide; toluene-4-sulfonic acid; orthoformic acid triethyl ester; pyridinium chlorochromate;
In
methanol; dimethyl sulfoxide; toluene;
DOI:10.1002/hlca.19810640750
