2-AMINO-6 H-DIBENZO[B,D]PYRAN-6-ONE

Base Information

• Chemical Name: 2-AMINO-6 H-DIBENZO[B,D]PYRAN-6-ONE
• CAS No.: 83527-99-5
• Molecular Formula: C13H9 N O2
• Molecular Weight: 211.22
• Hs Code.: 2922399090
• Mol file: 83527-99-5.mol

Synonyms:2-Biphenylcarboxylicacid, 5'-amino-2'-hydroxy-, d-lactone (6CI); 2-Amino-6H-dibenzo[b,d]pyran-6-one; NSC 405762; SG 00611

Chemical Property of 2-AMINO-6 H-DIBENZO[B,D]PYRAN-6-ONE

Chemical Property:

• Vapor Pressure: 9.05E-08mmHg at 25°C
• Melting Point: 190-191 °C(lit.)
• Refractive Index: 1.692
• Boiling Point: 435°C at 760 mmHg
• Flash Point: 259.2°C
• PSA: 56.23000
• Density: 1.354g/cm³
• LogP: 3.10960

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Amino-3,4-benzocoumarin 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6-Amino-3,4-benzocoumarin may be used in chemical synthesis.

Technology Process of 2-AMINO-6 H-DIBENZO[B,D]PYRAN-6-ONE

There total 6 articles about 2-AMINO-6 H-DIBENZO[B,D]PYRAN-6-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

6-nitro-3,4-benzocoumarin (6623-66-1) → 2-amino-6H-benzo[c]chromen-6-one (83527-99-5)

Guidance literature:

With indium; ammonium chloride; In ethanol; water; for 22h; Heating;

DOI:10.1080/00397910008087002

Reference yield: 52.0%

3'-Azido-biphenyl-2-carboxylic acid methyl ester (83527-98-4) → 2-amino-6H-benzo[c]chromen-6-one (83527-99-5) + 1-Amino-benzo[c]chromen-6-one

Guidance literature:

With trifluorormethanesulfonic acid; In tetrachloromethane; at 40 ℃; for 30h;

DOI:10.1021/jo00145a056

Reference yield: 34.0%

o-methoxycarbonylbenzenediazonium chloride (35358-78-2) + 4-amino-phenol (123-30-8) → 2-amino-6H-benzo[c]chromen-6-one (83527-99-5)

Guidance literature:

4-amino-phenol; With hydrogenchloride; sodium nitrite; In water; for 0.333333h; Inert atmosphere;

o-methoxycarbonylbenzenediazonium chloride; With titanium(III) chloride; In water; at 20 ℃; for 0.25h; Inert atmosphere;

DOI:10.1002/cmdc.201300369

upstream raw materials:

2-phenylazo-benzo[c]chromen-6-one

3'-Azido-biphenyl-2-carboxylic acid methyl ester

6-nitro-3,4-benzocoumarin

6H-benzo[c]chromen-6-one

Downstream raw materials:

C₂₀H₁₄BNO₅

Refernces

• 1、 Wetzel, Alexander,Pratsch, Gerald,Kolb, Roman,Heinrich, Markus R.. "Radical arylation of phenols, phenyl ethers, and furans". experimental part. p. 2547 - 2556. Retrieved 2010/06/17.
• 2、 Banik,Suhendra,Banik,Becker. "Indium/ammonium chloride mediated selective reduction of aromatic nitro compounds: Practical synthesis of 6-aminochrysene". . p. 3745 - 3754. Retrieved 2007/10/03.