2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone

Base Information

• Chemical Name: 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone
• CAS No.: 66927-58-0
• Molecular Formula: C₁₈H₁₄N₄O₄
• Molecular Weight: 350.334
• Mol file: 66927-58-0.mol

Synonyms:2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone

Chemical Property of 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone

There total 6 articles about 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

6(5H)-benzocyclooctenone (66927-57-9) + (2,4-dinitro-phenyl)-hydrazine (119-26-6) → 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone (66927-58-0)

Guidance literature:

sulfuric acid; In methanol;

DOI:10.1016/S0040-4020(01)88542-2

Reference yield:

5,6-dibromo-5,6-dihydrobenzocyclooctene (23697-02-1) → 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone (66927-58-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 19 percent / tetrahydrofuran / 1 h / Ambient temperature

2: acetic acid / 22 h / 100 °C

3: cond. H₂SO₄ / tetrahydrofuran; H₂O / Heating

4: 91 percent / cond. H₂SO₄ / methanol

With sulfuric acid; sulfuric acid; In tetrahydrofuran; methanol; water; acetic acid;

DOI:10.1016/S0040-4020(01)88542-2

Reference yield:

benzocyclooctene (265-49-6) → 2,4-dinitrophenylhydrazone of 6(5H)-benzocyclooctenone (66927-58-0)

Guidance literature:

Multi-step reaction with 5 steps

1: Br₂ / CH₂Cl₂ / 0.17 h / -70 °C

2: 19 percent / tetrahydrofuran / 1 h / Ambient temperature

3: acetic acid / 22 h / 100 °C

4: cond. H₂SO₄ / tetrahydrofuran; H₂O / Heating

5: 91 percent / cond. H₂SO₄ / methanol

With sulfuric acid; bromine; sulfuric acid; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid;

DOI:10.1016/S0040-4020(01)88542-2

upstream raw materials:

6(5H)-benzocyclooctenone

(2,4-dinitro-phenyl)-hydrazine

benzocyclooctene

5,6-dibromo-5,6-dihydrobenzocyclooctene

Refernces