(4-PHENYLBUTYL)PHOSPHINIC ACID

Base Information

• Chemical Name: (4-PHENYLBUTYL)PHOSPHINIC ACID
• CAS No.: 86552-32-1
• Molecular Formula: C10H15 O2 P
• Molecular Weight: 198.202
• Mol file: 86552-32-1.mol

Synonyms:(4-Phenylbutyl)phosphinicacid; (4-Phenylbutyl)phosphonous acid

Chemical Property of (4-PHENYLBUTYL)PHOSPHINIC ACID

Chemical Property:

• Boiling Point: 361.2±35.0 °C(Predicted)
• PKA: 3.41±0.10(Predicted)

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-PHENYLBUTYL)PHOSPHINIC ACID

There total 7 articles about (4-PHENYLBUTYL)PHOSPHINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-Phenylbut-1-ene (768-56-9) → (4-phenylbutyl)phosphinic acid (86552-32-1)

Guidance literature:

With polystyrene-NH-CO-nixantphos; hypophosphorous acid; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In acetonitrile; Heating;

DOI:10.1021/ol0484198

Reference yield: 96.0%

4-phenylbutyl phosphine → (4-phenylbutyl)phosphinic acid (86552-32-1)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; water;

Reference yield:

sodium hypophosphite (10039-56-2) + 4-Phenylbut-1-ene (768-56-9) → (4-phenylbutyl)phosphinic acid (86552-32-1)

Guidance literature:

With triethyl borane; In methanol; at 20 ℃; for 4h;

upstream raw materials:

4-Phenylbut-1-ene

sodium hypophosphite

diethyl ether

azobisisobutyronitrile

Downstream raw materials:

(1-Hydroxy-1,3-dimethyl-but-2-enyl)-(4-phenyl-butyl)-phosphinic acid

4-[Hydroxy-(4-phenylbutyl)phosphinyl]-4,4-dimethyl-2-butanone

(4-phenylbutyl)phosphonous acid 1-adamantylamine salt

(4-Phenyl-butyl)-phosphinic acid tert-butyl ester

Refernces

• 1、 -. "Method for preparation of alkyl phosphonyl compound from peroxide". Paragraph 0034; 0035. . Retrieved 2019/10/01.
• 2、 Troupa, Panagiota,Katsiouleri, Georgia,Vassiliou, Stamatia. "Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H -Phosphinic Acids without Added Metal or Radical Initiator". supporting information. p. 2714 - 2719. Retrieved 2015/11/27.