2',3'-di-O-benzoyluridine

Base Information

• Chemical Name: 2',3'-di-O-benzoyluridine
• CAS No.: 40733-60-6
• Molecular Formula: C₂₃H₂₄N₂O₆
• Molecular Weight: 424.453
• Mol file: 40733-60-6.mol

Synonyms:2',3'-di-O-benzoyluridine

Chemical Property of 2',3'-di-O-benzoyluridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',3'-di-O-benzoyluridine

There total 2 articles about 2',3'-di-O-benzoyluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl chloride (100-44-7) + 5'-O-trityluridine (6554-10-5) → 2',3'-di-O-benzoyluridine (40733-60-6)

Guidance literature:

With 1,4-dioxane; potassium hydroxide; benzene; anschl. mit wss. Essigsaeure;

DOI:10.1039/jr9560003459

Reference yield:

→ O2',O3'-dibenzyl-uridine (40733-60-6)

Guidance literature:

B. nach Michelson, Todd, Soc. 1956, 3459;

Reference yield: 95.0%

2',3'-di-O-benzoyluridine (40733-60-6) → 5'-azido-2',3'-di-O-benzyl-5'-deoxyuridine (262286-51-1)

Guidance literature:

With sodium azide; carbon tetrabromide; triphenylphosphine; In N,N-dimethyl-formamide; at 90 ℃; for 15h;

DOI:10.1021/jo991206p

upstream raw materials:

benzyl chloride

5'-O-trityluridine

Downstream raw materials:

5'-azido-2',3'-di-O-benzyl-5'-deoxyuridine

(E)-4-((2R,3S,4R,5S,6R)-3-Acetylamino-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-but-2-enoic acid (2R,3R,4R,5R)-3,4-bis-benzyloxy-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester

5'-amino-2',3'-di-O-benzyl-5'-deoxy-uridine

(E)-4-((2R,3S,4R,5S,6R)-3-Acetylamino-4,5-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-but-2-enoic acid [(2R,3R,4R,5R)-3,4-bis-benzyloxy-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-amide