(2-ACETOXYETHOXY)-METHYL BROMIDE

Base Information

• Chemical Name: (2-ACETOXYETHOXY)-METHYL BROMIDE
• CAS No.: 81777-40-4
• Molecular Formula: C5H9 Br O3
• Molecular Weight: 197.029
• Mol file: 81777-40-4.mol

Synonyms:Ethanol,2-(bromomethoxy)-, acetate (9CI); 2-Acetoxyethoxymethyl bromide; NSC 637534

Chemical Property of (2-ACETOXYETHOXY)-METHYL BROMIDE

Chemical Property:

• Boiling Point: 221.7±15.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.469±0.06 g/cm3(Predicted)
• LogP: 0.91850

Purity/Quality:

97% ^*data from raw suppliers

(2-ACETOXYETHOXY)-METHYL BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-ACETOXYETHOXY)-METHYL BROMIDE

There total 1 articles about (2-ACETOXYETHOXY)-METHYL BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N2-acetyl-7-benzylguanine (17495-10-2) → 9-(2-acetoxyethoxy)methyl-7-benzyl-N2-acetylguaninium bromide + 2-acetoxyethoxymethyl bromide (81777-40-4)

Guidance literature:

In N,N-dimethyl-formamide;

Reference yield: 76.0%

4-(4-chlorophenyl)-6-oxo-2-(pyridin-2-yl)-1,6-dihydropyridine-5-carbonitrile (906652-90-2) + 2-acetoxyethoxymethyl bromide (81777-40-4) → C22H18ClN3O4 (1572233-19-2)

Guidance literature:

4-(4-chlorophenyl)-6-oxo-2-(pyridin-2-yl)-1,6-dihydropyridine-5-carbonitrile; With potassium carbonate; In N,N-dimethyl-formamide; for 1h;

2-acetoxyethoxymethyl bromide; In N,N-dimethyl-formamide; Reflux;

DOI:10.1016/j.ejmech.2013.12.055

Reference yield: 75.0%

4-(4-fluorophenyl)-2-oxo-6-(p-tolyl)-1,2-dihydropyridine-3-carbonitrile + 2-acetoxyethoxymethyl bromide (81777-40-4) → 2-(((3-cyano-4-(4-fluorophenyl)-6-(p-tolyl)pyridin-2-yl)oxy)methoxy)ethyl acetate

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 20h; Reflux;

DOI:10.2174/1573406414666180522123524

upstream raw materials:

N²-acetyl-7-benzylguanine

Downstream raw materials:

4-amino-3-cyano-1-<(2-acetoxyethoxy)methyl>pyrazolo<3,4-d>pyrimidine

4-amino-5-cyano-7-<(2-acetoxyethoxy)methyl>pyrrolo<2,3-d>pyrimidine

4-amino-5-cyano-1-<(2-acetoxyethoxy)methyl>pyrrolo<2,3-d>pyrimidine

trimethylsilyl bromide

Refernces