C₁₀H₁₁ClO

Base Information

• Chemical Name: C₁₀H₁₁ClO
• CAS No.: 167958-19-2
• Molecular Formula: C₁₀H₁₁ClO
• Molecular Weight: 182.65
• Mol file: 167958-19-2.mol

Synonyms:C₁₀H₁₁ClO

Chemical Property of C₁₀H₁₁ClO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₁₁ClO

There total 2 articles about C₁₀H₁₁ClO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

3-chloro-2-methylcinnamaldehyde (35811-93-9) → C10H11ClO (167958-19-2) + (S)-2-methyl-3-phenylpropan-1-ol (7384-80-7,77943-96-5,78964-61-1,22436-06-2) + (Z)-(2S,3R)-5-chloro-4-methyl-5-phenylpent-4-ene-2,3-diol (1206614-89-2)

Guidance literature:

With baker's yeast; D-glucose; In ethanol; water; at 20 ℃; for 96h; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/ejoc.200900827

Reference yield:

3-chloro-2-methylcinnamaldehyde (35811-93-9) → C10H11ClO (167958-19-2)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1002/chem.200601418

Reference yield:

C10H11ClO (167958-19-2) → 3-methyl-1,4-diphenyl-2H-phosphete 1-oxide

Guidance literature:

Multi-step reaction with 2 steps

1.1: Bu₃P

2.1: [Cp₂Ti{P(OEt)3}2] / tetrahydrofuran / 1 h / 25 °C

2.2: 60 percent / tetrahydrofuran / 1 h / Heating

With tributylphosphine; In tetrahydrofuran;

DOI:10.1002/chem.200601418

upstream raw materials:

3-chloro-2-methylcinnamaldehyde

Downstream raw materials:

C₁₆H₁₅ClS

Refernces

• 1、 Shono, Tomohiro,Kurashige, Rie,Mukaiyama, Ryo,Tsubouchi, Akira,Takeda, Takeshi. "Titanacyclobutenes or titanium vinyl carbene complexes? Reactivity of organotitanium species generated by the reaction of γ-chloroallyl sulfides with a titanocene(II) reagent". . p. 4074 - 4080. Retrieved 2008/02/08.