2,3-Dimethyl-piperazine

Base Information

• Chemical Name: 2,3-Dimethyl-piperazine
• CAS No.: 84468-52-0
• Molecular Formula: C6H14 N2
• Molecular Weight: 114.191
• Hs Code.: 2933599090
• Mol file: 84468-52-0.mol

Synonyms:2,3-Dimethylpiperazine

Chemical Property of 2,3-Dimethyl-piperazine

Chemical Property:

• Melting Point: 82-88°C
• PSA: 24.06000
• LogP: 0.61380
• Sensitive.: Air Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-dimethylpiperazine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Dimethyl-piperazine

There total 9 articles about 2,3-Dimethyl-piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.2%

2,3-dimethylpyrazine (5910-89-4) → 2,3-dimethylpiperazine (84468-52-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 40 ℃; for 72h;

Reference yield:

5,6-dimethyl-2,3-dihydropyrazine (15986-92-2) → cis-2,3-dimethylpiperazine (57193-34-7) + trans-2,3-dimethylpiperazine (57193-34-7,57193-35-8,84468-52-0)

Guidance literature:

With palladium on activated charcoal; ethanol; at 160 ℃; under 56634.1 Torr; Hydrogenation;

Reference yield:

→ cis-2,3-dimethylpiperazine (57193-34-7) + trans-2,3-dimethylpiperazine (57193-34-7,57193-35-8,84468-52-0)

Guidance literature:

With 1,4-dioxane; hydrogen; nickel; at 200 ℃; under 73550.8 Torr;

upstream raw materials:

5,6-dimethyl-2,3-dihydropyrazine

2,3-dimethylpyrazine

ethylenediamine

trans-2,3-dimethylpiperazine

Downstream raw materials:

(+)-trans-2,3-dimethyl-piperazine

(-)-trans-2,3-dimethyl-piperazine

(+/-)-2r,3t-dimethyl-1,4-bis-(toluene-4-sulfonyl)-piperazine

2,3-dimethylpyrazine

Refernces

• 1、 -. "Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders". Page/Page column 75. . Retrieved 2010/02/14.