C₁₇H₁₁ClN₂O

Base Information

• Chemical Name: C₁₇H₁₁ClN₂O
• CAS No.: 1435936-71-2
• Molecular Formula: C₁₇H₁₁ClN₂O
• Molecular Weight: 294.74
• Mol file: 1435936-71-2.mol

Synonyms:C₁₇H₁₁ClN₂O

Chemical Property of C₁₇H₁₁ClN₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₁ClN₂O

There total 8 articles about C₁₇H₁₁ClN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

→ C17H11ClN2O (1435936-71-2)

Guidance literature:

With N-chloro-succinimide; In tetrahydrofuran; tetrachloromethane; at 45 ℃; for 2h;

Reference yield:

C22H19ClN2O3 → C17H11ClN2O (1435936-71-2)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; Inert atmosphere;

DOI:10.5012/bkcs.2013.34.2.357

Reference yield:

N-benzoyltryptamine (4753-09-7) → C17H11ClN2O (1435936-71-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran / 0 °C / Inert atmosphere

2: triphenylphosphine; triethylamine / dichloromethane / 20 °C / Inert atmosphere

3: dmap; triethylamine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

4: N-chloro-succinimide; tetrachloromethane / tetrahydrofuran / 20 °C / Inert atmosphere

5: trifluoroacetic acid / 20 °C / Inert atmosphere

With tetrachloromethane; dmap; N-chloro-succinimide; triethylamine; triphenylphosphine; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane;

DOI:10.5012/bkcs.2013.34.2.357

upstream raw materials:

tryptamine

N-benzoyltryptamine

benzoic acid

N-[2-(1H-indol-3-yl)-2-oxoethyl]benzamide

Refernces

• 1、 Lee, Jong Seok,Shin, Junho,Lee, Hyi-Seung,Shin, Hee Jae,Lee, Yeon-Ju. "A concise and rapid approach to the marine natural product streptochlorin and its analogues". . p. 357 - 358. Retrieved 2013/08/25.