5-Chloro-2-hydrazinopyrimidine

Base Information

• Chemical Name: 5-Chloro-2-hydrazinopyrimidine
• CAS No.: 823-90-5
• Molecular Formula: C4H5 Cl N4
• Molecular Weight: 144.564
• Hs Code.: 2933990090
• European Community (EC) Number: 801-845-5
• ChEMBL ID: CHEMBL3793856
• DSSTox Substance ID: DTXSID40482902
• Mol file: 823-90-5.mol

Synonyms:5-Chloro-2-hydrazinopyrimidine;823-90-5;5-CHLORO-2-HYDRAZINYLPYRIMIDINE;(5-chloropyrimidin-2-yl)hydrazine;2(1H)-Pyrimidinone, 5-chloro-, hydrazone (9CI);CHEMBL3793856;SCHEMBL15360097;DTXSID40482902;WUDNSGDMTFEQIF-UHFFFAOYSA-N;MFCD09754100;AKOS005136173;AB51525;DS-15425;5-Chloro-2-hydrazono-1,2-dihydropyrimidine;CS-0168248;2(1H)-Pyrimidinone,5-chloro-,hydrazone(9ci);EN300-275883;F88137

Chemical Property of 5-Chloro-2-hydrazinopyrimidine

Chemical Property:

• PSA: 63.83000
• LogP: 1.18890
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 144.0202739
• Heavy Atom Count: 9
• Complexity: 80.6

Purity/Quality:

98%min ^*data from raw suppliers

5-Chloro-2-hydrazinylpyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=NC(=N1)NN)Cl

Technology Process of 5-Chloro-2-hydrazinopyrimidine

There total 2 articles about 5-Chloro-2-hydrazinopyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichloropyrimidine (22536-67-0) → 2-hydrazineyl-5-chloropyrimidine (823-90-5)

Guidance literature:

With hydrazine hydrate; In ethanol; at 60 ℃;

DOI:10.1016/j.bmcl.2016.03.048

Reference yield:

→ 2-hydrazineyl-5-chloropyrimidine (823-90-5)

Guidance literature:

2-Nitramino-5-chlorpyrimidin, H2NNH2*H2O;

Reference yield: 6.68%

ethyl 5-formyl-2',4'-dimethyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-4-carboxylate + 2-hydrazineyl-5-chloropyrimidine (823-90-5) → 2-(5-chloropyrimidin-2-yl)-6-(2,4-dimethylphenyl)-5,6,7,8-tetrahydrophthalazin-1(2H)-one

Guidance literature:

With acetic acid; In ethanol; at 100 ℃; for 12h;

upstream raw materials:

2,5-dichloropyrimidine

Refernces