benzyl 2,4,6-triacetoxyphenyl ketone

Base Information

• Chemical Name: benzyl 2,4,6-triacetoxyphenyl ketone
• CAS No.: 34544-87-1
• Molecular Formula: C₂₀H₁₈O₇
• Molecular Weight: 370.359
• Mol file: 34544-87-1.mol

Synonyms:benzyl 2,4,6-triacetoxyphenyl ketone

Chemical Property of benzyl 2,4,6-triacetoxyphenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 2,4,6-triacetoxyphenyl ketone

There total 4 articles about benzyl 2,4,6-triacetoxyphenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1-acetoxy-1-(2,4,6-triacetoxyphenyl)-2-phenylethene → benzyl 2,4,6-triacetoxyphenyl ketone (34544-87-1) + benzyl 2,6-diacetoxy-4-hydroxyphenyl ketone

Guidance literature:

With butan-1-ol; porcine pancreatic lipase (Type-II); In tetrahydrofuran; at 42 - 45 ℃; for 72h;

DOI:10.1016/S0968-0896(97)10010-4

Reference yield:

2-phenyl-2',4',6'-trihydroxyacetophenone (727-71-9) → benzyl 2,4,6-triacetoxyphenyl ketone (34544-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: 55 percent / n-butanol / porcine pancreatic lipase (Type-II) / tetrahydrofuran / 72 h / 42 - 45 °C

With pyridine; butan-1-ol; porcine pancreatic lipase (Type-II); In tetrahydrofuran; 1: Acetylation / 2: Deacetylation;

DOI:10.1016/S0968-0896(97)10010-4

Reference yield:

2-phenyl-2',4',6'-trihydroxyacetophenone (727-71-9) + acetic anhydride (108-24-7) → benzyl 2,4,6-triacetoxyphenyl ketone (34544-87-1)

Guidance literature:

With perchloric acid;

upstream raw materials:

2-phenyl-2',4',6'-trihydroxyacetophenone

acetic anhydride

acetyl chloride

Downstream raw materials:

2,4,6-Triacetoxy-desoxybenzoin-enolacetat

5,7-dihydroxy-2-methylisoflavone

Refernces