C₁₆H₂₁ClO₄

Base Information

• Chemical Name: C₁₆H₂₁ClO₄
• CAS No.: 1262033-06-6
• Molecular Formula: C₁₆H₂₁ClO₄
• Molecular Weight: 312.793
• Mol file: 1262033-06-6.mol

Synonyms:C₁₆H₂₁ClO₄

Chemical Property of C₁₆H₂₁ClO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₁ClO₄

There total 4 articles about C₁₆H₂₁ClO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-chlorophenylacetate (53088-68-9) + 5-iodomethyl-2,2-dimethyl-1,3-dioxane (97827-17-3) → C16H21ClO4 (1262033-06-6)

Guidance literature:

With lithium diisopropyl amide;

DOI:10.1016/j.bmcl.2010.10.052

Reference yield:

2,2-dimethyl-5-hydroxymethyl-1,3-dioxane (4728-12-5) → C16H21ClO4 (1262033-06-6)

Guidance literature:

Multi-step reaction with 2 steps

1: iodine; triphenylphosphine

2: lithium diisopropyl amide

With iodine; triphenylphosphine; lithium diisopropyl amide;

DOI:10.1016/j.bmcl.2010.10.052

Reference yield:

2,2-Dimethyl-1,3-dioxacyclohexane-5,5-dicarboxylic acid,diethyl ester (51335-75-2) → C16H21ClO4 (1262033-06-6)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium chloride / dimethyl sulfoxide

2: lithium aluminium tetrahydride

3: iodine; triphenylphosphine

4: lithium diisopropyl amide

With lithium aluminium tetrahydride; iodine; triphenylphosphine; sodium chloride; lithium diisopropyl amide; In dimethyl sulfoxide;

DOI:10.1016/j.bmcl.2010.10.052

upstream raw materials:

methyl 3-chlorophenylacetate

5-iodomethyl-2,2-dimethyl-1,3-dioxane

2,2-dimethyl-5-hydroxymethyl-1,3-dioxane

2,2-Dimethyl-1,3-dioxacyclohexane-5,5-dicarboxylic acid,diethyl ester

Downstream raw materials:

C₁₂H₁₃ClO₃

C₁₃H₁₇ClO₄

C₁₂H₁₁ClO₃

C₁₄H₁₃ClO₄

Refernces