N-cyclopentyl-N~2~-(2-ethoxyphenyl)-N~2~-(phenylsulfonyl)glycinamide

Base Information

• Chemical Name: N-cyclopentyl-N~2~-(2-ethoxyphenyl)-N~2~-(phenylsulfonyl)glycinamide
• CAS No.: 6013-47-4
• Molecular Formula: C14H14 O S
• Molecular Weight: 230.331
• Mol file: 6013-47-4.mol

Synonyms:Anisole,p-(p-tolylthio)- (7CI,8CI); 4-Anisyl 4-tolyl sulfide; p-Anisyl p-tolyl sulfide

Chemical Property of N-cyclopentyl-N~2~-(2-ethoxyphenyl)-N~2~-(phenylsulfonyl)glycinamide

Chemical Property:

• Density: 1.27g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-cyclopentyl-N~2~-(2-ethoxyphenyl)-N~2~-(phenylsulfonyl)glycinamide

There total 103 articles about N-cyclopentyl-N~2~-(2-ethoxyphenyl)-N~2~-(phenylsulfonyl)glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Methoxybenzenethiol (696-63-9) + 4-tolyl iodide (624-31-7) → 4-methylphenyl 4-methoxyphenyl sulfide (6013-47-4)

Guidance literature:

With 1,10-Phenanthroline; caesium carbonate; manganese(ll) chloride; In toluene; at 135 ℃; for 48h; Inert atmosphere;

DOI:10.1002/asia.201300045

Reference yield: 99.0%

4-Methoxybenzenethiol (696-63-9) + para-chlorotoluene (106-43-4) → 4-methylphenyl 4-methoxyphenyl sulfide (6013-47-4)

Guidance literature:

With Pd(CyPF-tBu)(Br)(C₆H₄-4-Me); potassium tert-butylate; In toluene; at 20 ℃; Inert atmosphere;

Reference yield: 97.0%

para-iodoanisole (696-62-8) + para-thiocresol (106-45-6) → 4-methylphenyl 4-methoxyphenyl sulfide (6013-47-4)

Guidance literature:

With 1,1'-binaphthalene-2,2'-diamine; copper(II) bis(trifluoromethanesulfonate); caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.01.022

upstream raw materials:

p-methoxybenzenediazonium

para-thiocresol

S,S-Bis-<4-methoxy-phenyl>-N-p-toluolsulfonyl-sulfilimin

C₂₁H₂₁NO₃S₂

Downstream raw materials:

3-[(4-methylphenyl)sulfanyl]-1H-indole

1-methoxy-4-(4-toluenesulfinyl)benzene

p-tolyl p-methoxyphenyl sulfone

4-hydroxyphenyl 4-tolyl sulfide

Refernces

• 1、 Pan, Lei,Cooke, Maria Victoria,Spencer, Amara,Laulhé, Sébastien. "Dimsyl Anion Enables Visible-Light-Promoted Charge Transfer in Cross-Coupling Reactions of Aryl Halides". supporting information. p. 420 - 425. Retrieved 2021/11/01.
• 2、 Zhou, Wen-Yan,Chen, Min,Zhang, Pei-Zhi,Jia, Ai-Quan,Zhang, Qian-Feng. "Methods, Syntheses and Characterization of Diaryl, Aryl Benzyl, and Dibenzyl Sulfides". . p. 301 - 310. Retrieved 2020/09/07.