(E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate

Base Information

• Chemical Name: (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate
• CAS No.: 475673-41-7
• Molecular Formula: C₁₅H₁₇F₉O₃S
• Molecular Weight: 448.35
• Mol file: 475673-41-7.mol

Synonyms:(E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate

Chemical Property of (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate

There total 1 articles about (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

Nonafluorobutanesulfonyl fluoride (375-72-4) + (2,6,6-trimethyl-1-cyclohexen-1-yl)acetaldehyde (472-66-2) → (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate (475673-41-7)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; for 1h; Heating;

DOI:10.1055/s-2002-32602

Reference yield: 100.0%

tri-n-butyl(vinyl)tin (7486-35-3) + (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate (475673-41-7) → 2-<(E,E)-buta-1',3'-dien-1'-yl>-1,3,3-trimethylcyclohexene (74423-06-6)

Guidance literature:

With triphenyl-arsane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1055/s-2002-32602

Reference yield: 100.0%

(E)-3-(tri-n-butylstannyl)-2-propen-1-ol (82994-41-0,81925-29-3,74141-12-1,74141-13-2) + (E)-2-(2,6,6-trimethylcyclohexen-1-yl)ethenyl nonafluorobutanesulfonate (475673-41-7) → 5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dien-1-ol (4808-04-2)

Guidance literature:

With triphenyl-arsane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

DOI:10.1055/s-2002-32602

upstream raw materials:

Nonafluorobutanesulfonyl fluoride

(2,6,6-trimethyl-1-cyclohexen-1-yl)acetaldehyde

Downstream raw materials:

2-<(E,E)-buta-1',3'-dien-1'-yl>-1,3,3-trimethylcyclohexene

ethyl (2E,4E)-5-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-2,4-dienoate

5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dien-1-ol

(E)-5-(2,6,6-trimethylcyclohex-1-enyl)pent-4-en-2-yn-1-ol

Refernces

• 1、 Wada, Akimori,Ieki, Yasuhiro,Nakamura, Saeko,Ito, Masayoshi. "Palladium-catalyzed coupling reaction of an enol nonaflate with (vinyl)tributylstannanes and acetylenes: A highly stereoselective synthesis of 8,18-13C2-labeled retinal". . p. 1581 - 1588. Retrieved 2007/10/03.