4-N-acetyl-N-methylaminoantipyrine

Base Information

• Chemical Name: 4-N-acetyl-N-methylaminoantipyrine
• CAS No.: 15421-74-6
• Molecular Formula: C₁₄H₁₇N₃O₂
• Molecular Weight: 259.308
• Mol file: 15421-74-6.mol

Synonyms:4-N-acetyl-N-methylaminoantipyrine

Chemical Property of 4-N-acetyl-N-methylaminoantipyrine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-N-acetyl-N-methylaminoantipyrine

There total 2 articles about 4-N-acetyl-N-methylaminoantipyrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-acetylaminoantipyrine (83-15-8) + methyl iodide (74-88-4) → 4-N-acetyl-N-methylaminoantipyrine (15421-74-6)

Guidance literature:

With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/bi101797v

Reference yield:

→ 4-N-acetyl-N-methylaminoantipyrine (15421-74-6)

Guidance literature:

4-Methylamino-antipyrin, Acetanhydrid, 20grad, 20 min;

Reference yield: 85.0%

4-N-acetyl-N-methylaminoantipyrine (15421-74-6) → 4-methylaminoantipyrine (519-98-2)

Guidance literature:

With hydrogenchloride; water; Reflux;

DOI:10.1021/bi101797v

upstream raw materials:

4-acetylaminoantipyrine

methyl iodide

Downstream raw materials:

4-methylaminoantipyrine

Refernces