C₂₃H₂₂O₇

Base Information

• Chemical Name: C₂₃H₂₂O₇
• CAS No.: 58084-82-5
• Molecular Formula: C₂₃H₂₂O₇
• Molecular Weight: 410.423
• Mol file: 58084-82-5.mol

Synonyms:C₂₃H₂₂O₇

Chemical Property of C₂₃H₂₂O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₂O₇

There total 14 articles about C₂₃H₂₂O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

7-(1,1-dimethylpropargyloxy)-5-hydroxy-2',4',5'-trimethoxyisoflavone (1446307-18-1) → C23H22O7 (58084-82-5)

Guidance literature:

With sodium hydride; In 5,5-dimethyl-1,3-cyclohexadiene; mineral oil; at 130 ℃; for 20h; regioselective reaction;

DOI:10.1002/ejoc.201201339

Reference yield: 40.0%

7-(1,1-dimethylpropargyloxy)-5-hydroxy-2',4',5'-trimethoxyisoflavone (1446307-18-1) → C23H22O7 (58084-82-5) + 5-hydroxy-2',4',5'-trimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone (3044-60-8)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; for 20h; Overall yield = 80 %; regioselective reaction; Inert atmosphere;

DOI:10.1002/ejoc.201201339

Reference yield:

2,4,5-trimethoxybenzeneacetonitrile (38444-50-7) → C23H22O7 (58084-82-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: zinc(II) chloride; hydrogenchloride / diethyl ether / 36 h / 0 - 20 °C / Cooling with ice

1.2: 3 h / Reflux

2.1: boron trifluoride diethyl etherate; methanesulfonyl chloride / 3.83 h / 20 - 90 °C

3.1: potassium carbonate; potassium iodide; copper(l) iodide / acetone / 3 h / Inert atmosphere; Reflux

4.1: sodium hydride / 5,5-dimethyl-1,3-cyclohexadiene; mineral oil / 20 h / 130 °C

With hydrogenchloride; copper(l) iodide; boron trifluoride diethyl etherate; sodium hydride; potassium carbonate; methanesulfonyl chloride; potassium iodide; zinc(II) chloride; In 5,5-dimethyl-1,3-cyclohexadiene; diethyl ether; acetone; mineral oil; 1.1: |Houben-Hoesch Phenol Acylation / 1.2: |Houben-Hoesch Phenol Acylation / 2.1: |Vilsmeier-Haack Formylation / 4.1: |Claisen Rearrangement;

DOI:10.1002/ejoc.201201339

upstream raw materials:

2',4',6'-trihydroxy-(2,4,5-trimethoxyphenyl)acetophenone

3,5-dihydroxyphenol

2,4,5-trimethoxybenzeneacetonitrile

asaraldehyde

Downstream raw materials:

2',4',5,5'-tetramethoxy-2,2-dimethylpyrano<5,6-g>isoflavone

C₂₂H₁₈O₇

Refernces