bis(N,N-diisopropylamino)phosphine

Base Information

• Chemical Name: bis(N,N-diisopropylamino)phosphine
• CAS No.: 86660-77-7
• Molecular Formula: C₁₂H₂₉N₂P
• Molecular Weight: 232.349
• Mol file: 86660-77-7.mol

Synonyms:bis(N,N-diisopropylamino)phosphine

Chemical Property of bis(N,N-diisopropylamino)phosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bis(N,N-diisopropylamino)phosphine

There total 2 articles about bis(N,N-diisopropylamino)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

bis(diisopropylamino)chlorophosphine (56183-63-2) + lithium diisopropyl amide (4111-54-0) → bis(N,N-diisopropylamino)phosphine (86660-77-7) + bis(dialkylaminophosphanyl)imine (350038-30-1)

Guidance literature:

In diethyl ether; at 20 ℃; for 12h;

DOI:10.1039/b009867l

Reference yield:

bis(diisopropylamino)chlorophosphine (56183-63-2) → tetrakis(diisopropylamino)diphosphane (128388-72-7) + bis(N,N-diisopropylamino)phosphine (86660-77-7) + bis(dialkylaminophosphanyl)imine (350038-30-1)

Guidance literature:

With lithium diisopropyl amide;

Reference yield: 95.0%

[Mn(cyclopentadienyl)(CO)2(CPh)]BPh4 + bis(N,N-diisopropylamino)phosphine (86660-77-7) → [Mn(cyclopentadienyl)(CO)(OCC(Ph)P((i-Pr)2N)2)] (1071224-72-0)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; byproducts: (DBUH)(BPh4); (N2); using Schlenk techniques; suspending of CpMn(CO)2(CPh)BPh4 in CH2Cl2 at -50°C, addn. of HP(Ni-Pr2)2 via syringe under stirring, monitoring by IR for 0.5 h, cooling to -80°C, treatment with DBU (1 equiv.), warming to room temp. for 1h; removal of solvent under vac., extn. with ether, filtration of combined extracts, removal of solvent under vac., washing with pentane, drying under vac.; elem. anal;

DOI:10.1021/om2000772

upstream raw materials:

bis(diisopropylamino)chlorophosphine

lithium diisopropyl amide

Downstream raw materials:

di-tert-butyl phosphite

bis(trimethylsiloxy)phosphine

formic acid [bis(N,N-diisopropylamino)phosphino]-β-(diphenylmethylsilyl)ethyl ester

3'-O-(N,N-diisopropylamino)phosphinoformic acid β-(diphenylmethylsilyl)ethyl ester 5'-O-di-p-anisylphenylmethyl-2'-deoxythymidine

Refernces

• 1、 Hund, Heike,Hund, Rolf-Dieter,Has, Senay,Roeschenthaler, Gerd-Volker. "Synthesis and reactions of the novel diphosphine, iPrN=C2". . p. 193. Retrieved 2007/10/03.