Technology Process of 7-methoxy-1-naphthylethyl benzenesulfonate
There total 5 articles about 7-methoxy-1-naphthylethyl benzenesulfonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine;
at -5 - 0 ℃;
for 3h;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) N-isopropylcyclohexylamine, n-butyllithium / 1.) THF, hexane, -75 deg C, 15 min, 2.) THF, hexane, -78 deg C, 1.5 h
2: 81 percent / 10percent Pd/C, 1,1-diphenylethylene, 1-methylnaphthalene / 3 h / 250 - 260 °C
3: 94 percent / lithium aluminum hydride / diethyl ether / Ambient temperature
4: pyridine / 2 h
With
pyridine; 1,1-Diphenylethylene; palladium on activated charcoal; lithium aluminium tetrahydride; n-butyllithium; N-cyclohexylisopropylamine; 1-Methylnaphthalene;
In
diethyl ether;
DOI:10.1021/jo00350a024
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / polyphosphoric acid / 0.12 h / 90 - 100 °C
2: 1.) N-isopropylcyclohexylamine, n-butyllithium / 1.) THF, hexane, -75 deg C, 15 min, 2.) THF, hexane, -78 deg C, 1.5 h
3: 81 percent / 10percent Pd/C, 1,1-diphenylethylene, 1-methylnaphthalene / 3 h / 250 - 260 °C
4: 94 percent / lithium aluminum hydride / diethyl ether / Ambient temperature
5: pyridine / 2 h
With
pyridine; 1,1-Diphenylethylene; palladium on activated charcoal; lithium aluminium tetrahydride; n-butyllithium; PPA; N-cyclohexylisopropylamine; 1-Methylnaphthalene;
In
diethyl ether;
DOI:10.1021/jo00350a024
