N-benzyl-N-methylbenzothioamide

Base Information

• Chemical Name: N-benzyl-N-methylbenzothioamide
• CAS No.: 73641-17-5
• Molecular Formula: C₁₅H₁₅NS
• Molecular Weight: 241.357
• Mol file: 73641-17-5.mol

Synonyms:N-benzyl-N-methylbenzothioamide

Chemical Property of N-benzyl-N-methylbenzothioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-methylbenzothioamide

There total 4 articles about N-benzyl-N-methylbenzothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

benzyl-methyl-amine (103-67-3) → N-methylthiobenzamide (5310-14-5) + N-benzyl-N-methylbenzothioamide (73641-17-5)

Guidance literature:

With sulfur; at 170 ℃; for 0.25h; Microwave irradiation; neat (no solvent);

DOI:10.1080/17415993.2011.640329

Reference yield: 64.0%

phenylmethanethiol (100-53-8) + benzyl-methyl-amine (103-67-3) → N-benzyl-N-methylbenzothioamide (73641-17-5)

Guidance literature:

With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; oxygen; copper dichloride; In toluene; at 100 ℃; for 18h; under 760.051 Torr;

DOI:10.1021/jo501378v

Reference yield: 63.0%

benzyl-methyl-amine (103-67-3) → N-benzyl-N-methylbenzothioamide (73641-17-5)

Guidance literature:

With sulfur; C₁₁H₁₉N₂O₂⁽¹⁺⁾*Cl₄Fe^(1-); oxygen; sodium phosphate; In neat (no solvent); at 100 ℃; for 1h; Microwave irradiation; Green chemistry;

DOI:10.1055/s-0037-1610179

upstream raw materials:

benzyl-methyl-amine

phenylmethanethiol

morpholine

Downstream raw materials:

N-methyldibenzylamine

(E)-1,2-diphenyl-ethene

β-(Methylphenylamino)zimtsaeurenitril

benzaldehyde

Refernces

• 1、 Wang, Xi,Ji, Miran,Lim, Seungyeon,Jang, Hye-Young. "Thiol as a synthon for preparing thiocarbonyl: Aerobic oxidation of thiols for the synthesis of thioamides". . p. 7256 - 7260. Retrieved 2014/08/18.