1-(trifluoromethylsulfanyl)-2-vinylbenzene

Base Information

• Chemical Name: 1-(trifluoromethylsulfanyl)-2-vinylbenzene
• CAS No.: 1309953-74-9
• Molecular Formula: C₉H₇F₃S
• Molecular Weight: 204.216
• Mol file: 1309953-74-9.mol

Synonyms:1-(trifluoromethylsulfanyl)-2-vinylbenzene

Chemical Property of 1-(trifluoromethylsulfanyl)-2-vinylbenzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-(trifluoromethylsulfanyl)-2-vinylbenzene

There total 2 articles about 1-(trifluoromethylsulfanyl)-2-vinylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2-((trifluoromethyl)thio)benzaldehyde (57830-48-5) + methyl-triphenylphosphonium iodide (2065-66-9) → 1-(trifluoromethylsulfanyl)-2-vinylbenzene (1309953-74-9)

Guidance literature:

methyl-triphenylphosphonium iodide; With potassium tert-butylate; In diethyl ether; at 0 ℃; for 0.25h; Inert atmosphere;

2-((trifluoromethyl)thio)benzaldehyde; In diethyl ether; for 3h; Inert atmosphere;

DOI:10.1021/acs.organomet.7b00677

Reference yield: 27.0%

vinylboronic acid dibutyl ester (6336-45-4) + 1-bromo-2-[(trifluoromethyl)sulfanyl]benzene (1644-72-0) → 1-(trifluoromethylsulfanyl)-2-vinylbenzene (1309953-74-9)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium hydroxide; In tetrahydrofuran; water; at 70 ℃; for 4h;

DOI:10.1021/om200323c

Reference yield: 72.0%

dichloro(1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylylidene)(benzylidene)bis(pyridine)ruthenium(II) + 1-(trifluoromethylsulfanyl)-2-vinylbenzene (1309953-74-9) → [(CN(mesityl)CH2CH2N(mesityl))Cl2Ru(=CHC6H4SCF3)]

Guidance literature:

In chloroform; soln. of Ru complex (1.1 equiv.) and ligand in CHCl3 was refluxed for 4.5 h; evapd.; chromd. (silica gel, acetone/CH2Cl2, 1/10);

DOI:10.1021/om200323c

upstream raw materials:

vinylboronic acid dibutyl ester

1-bromo-2-[(trifluoromethyl)sulfanyl]benzene

2-((trifluoromethyl)thio)benzaldehyde

methyl-triphenylphosphonium iodide

Refernces

• 1、 Ginzburg, Yakov,Anaby, Aviel,Vidavsky, Yuval,Diesendruck, Charles E.,Ben-Asuly, Amos,Goldberg, Israel,Lemcoff, N. Gabriel. "Widening the latency gap in chelated ruthenium olefin metathesis catalysts". experimental part. p. 3430 - 3437. Retrieved 2011/08/07.