N'-hydroxy-4-nitrobenzimidamide

Base Information

• Chemical Name: N'-hydroxy-4-nitrobenzimidamide
• CAS No.: 192332-48-2
• Molecular Formula: C₇H₇N₃O₃
• Molecular Weight: 181.151
• Mol file: 192332-48-2.mol

Synonyms:N'-hydroxy-4-nitrobenzimidamide

Chemical Property of N'-hydroxy-4-nitrobenzimidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N'-hydroxy-4-nitrobenzimidamide

There total 29 articles about N'-hydroxy-4-nitrobenzimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-nitrobenzonitrile (619-72-7) → N'-hydroxy-4-nitrobenzimidamide (192332-48-2)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; water; at 85 ℃; for 2h; Inert atmosphere;

DOI:10.1002/ejoc.201501056

Reference yield: 98.0%

4-nitrobenzonitrile (619-72-7) → N-hydroxy-4-nitrobenzamidine (1613-86-1,192332-48-2)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; water; at 85 ℃; for 2h; Inert atmosphere;

Reference yield: 98.0%

4-nitrobenzonitrile (619-72-7) → (Z)-4-nitrobenzamidoxime (192332-48-2)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; water; at 20 ℃; Inert atmosphere;

DOI:10.1039/c8nj06242k

upstream raw materials:

4-nitrobenzohydroximoyl chloride

N,N'-bis(trimethylsilyl)sulfurdiimide

p-nitrobenzonitrile oxide

4-(4-Nitro-phenyl)-2λ⁴-[1,2,3,5]oxathiadiazol-2-ylamine

Downstream raw materials:

3-p-nitrophenyl-4,5-dihydro-1,2,4-oxadiazol-5-one

N-ethoxycarbonyloxy-4-nitro-benzamidine

5-methyl-3-(4-nitro-phenyl)-2⁽⁴⁾,5-dihydro-[1,2,4]oxadiazole

1-[3-(4-nitro-phenyl)-[1,2,4]oxadiazol-5-yl]-propan-2-one

Refernces

• 1、 . "-". . . Retrieved .
• 2、 Singh, Amita,Kociok-K?hn, Gabriele,Trivedi, Manoj,Chauhan, Ratna,Kumar, Abhinav,Gosavi, Suresh W.,Terashima, Chiaki,Fujishima, Akira. "Ferrocenylethenyl-substituted oxadiazoles with phenolic and nitro anchors as sensitizers in dye sensitized solar cells". . p. 4745 - 4756. Retrieved 2019.
• 3、 Abdelhamid, Antar A.,Gomaa, Hesham A. M.,Gouda, Ahmed M.,Kamal, Islam,Marzouk, Adel A.,Moustafa, Amr H.,Youssif, Bahaa G. M.. "Design and synthesis of new triarylimidazole derivatives as dual inhibitors of BRAFV600E/p38α with potential antiproliferative activity". . . Retrieved 2021/12/30.
• 4、 Shkineva, Tatyana K.,Vatsadze, Irina A.,Khoranyan, Tigran E.,Lipilin, Dmitry L.,Pivkina, Alla N.,Dalinger, Igor L.. "Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives". . p. 828 - 836. Retrieved 2021/09/20.