Technology Process of 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI)
There total 5 articles about 5-Pyrimidinamine, 2-chloro-4-methyl- (9CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen; triethylamine;
In
ethanol; water;
for 8h;
under 1034.32 Torr;
- Guidance literature:
-
With
ammonium chloride; zinc;
In
methanol;
at 70 ℃;
for 50h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sulfuric acid; nitric acid / 12 h / -2 - 35 °C
2: trichlorophosphate; N,N-dimethyl-aniline / N,N-dimethyl-formamide / 8 h / 120 °C
3: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C / 2068.65 Torr
4: palladium on activated charcoal; hydrogen; triethylamine / water; ethanol / 8 h / 1034.32 Torr
With
sulfuric acid; palladium on activated charcoal; hydrogen; nitric acid; N,N-dimethyl-aniline; triethylamine; trichlorophosphate;
In
ethanol; water; ethyl acetate; N,N-dimethyl-formamide;