Technology Process of methyl [4-fluoro-2-(3-fluorobenzyl)phenyl] acetate
There total 6 articles about methyl [4-fluoro-2-(3-fluorobenzyl)phenyl] acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 51 percent / CrO3 / aq. methanol / 3 h / 35 °C
2: 99 percent / H2SO4 / 16 h / Heating
3: 98 percent / hydrogen / Pd/C / acetic acid / 5 h / 70 °C / 3620.13 Torr
With
chromium(VI) oxide; sulfuric acid; hydrogen;
palladium on activated charcoal;
In
methanol; acetic acid;
DOI:10.1002/ejoc.200700200
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / p-toluenesulfonic acid / toluene / 3 h / Heating
2: 51 percent / CrO3 / aq. methanol / 3 h / 35 °C
3: 99 percent / H2SO4 / 16 h / Heating
4: 98 percent / hydrogen / Pd/C / acetic acid / 5 h / 70 °C / 3620.13 Torr
With
chromium(VI) oxide; sulfuric acid; hydrogen; toluene-4-sulfonic acid;
palladium on activated charcoal;
In
methanol; acetic acid; toluene;
DOI:10.1002/ejoc.200700200
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 99 percent / H2SO4 / 16 h / Heating
2: 98 percent / hydrogen / Pd/C / acetic acid / 5 h / 70 °C / 3620.13 Torr
With
sulfuric acid; hydrogen;
palladium on activated charcoal;
In
acetic acid;
DOI:10.1002/ejoc.200700200
