C₁₁H₂₀ClNO₃S

Base Information

• Chemical Name: C₁₁H₂₀ClNO₃S
• CAS No.: 1195758-84-9
• Molecular Formula: C₁₁H₂₀ClNO₃S
• Molecular Weight: 281.804
• Mol file: 1195758-84-9.mol

Synonyms:C₁₁H₂₀ClNO₃S

Chemical Property of C₁₁H₂₀ClNO₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₂₀ClNO₃S

There total 7 articles about C₁₁H₂₀ClNO₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H21NO4S (342578-12-5) → C11H20ClNO3S (1195758-84-9)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

C12H23NO3S → C11H20ClNO3S (1195758-84-9)

Guidance literature:

Multi-step reaction with 4 steps

1: ammonium molybdate tetrahydrate; dihydrogen peroxide / water / Inert atmosphere

2: sodium methylate / toluene; methanol / Inert atmosphere

3: water / Inert atmosphere

4: N,N-dimethyl-formamide; thionyl chloride / toluene / 50 °C / Inert atmosphere; Large scale

With thionyl chloride; ammonium molybdate tetrahydrate; water; dihydrogen peroxide; sodium methylate; N,N-dimethyl-formamide; In methanol; water; toluene;

DOI:10.1021/acs.oprd.5b00023

Reference yield:

4-tert-butylsulfinamidocyclohexanecarboxylic acid → C11H20ClNO3S (1195758-84-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide; sulfuric acid; sodium tungstate (VI) dihydrate / water / 25 °C / pH 9.0 / Inert atmosphere; Large scale

2: N,N-dimethyl-formamide; thionyl chloride / toluene / 50 °C / Inert atmosphere; Large scale

With thionyl chloride; sodium tungstate (VI) dihydrate; sulfuric acid; dihydrogen peroxide; N,N-dimethyl-formamide; In water; toluene;

DOI:10.1021/acs.oprd.5b00023

upstream raw materials:

C₁₁H₂₁NO₄S

4-aminocyclohexanecarboxylic acid

Downstream raw materials:

C₁₃H₂₃N₃O₃S

C₁₄H₂₂F₃N₃O₅S₂

C₁₉H₂₆FN₃O₂S

C₁₉H₂₅FIN₃O₂S

Refernces

• 1、 -. "COMPOUND HAVING NPY Y5 RECEPTOR ANTAGONIST ACTIVITY". Page/Page column 45-46. . Retrieved 2011/02/25.