(E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride

Base Information

• Chemical Name: (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride
• CAS No.: 197144-97-1
• Molecular Formula: C₁₅H₂₃NO*ClH
• Molecular Weight: 269.815
• Mol file: 197144-97-1.mol

Synonyms:(E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride

Chemical Property of (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride

There total 2 articles about (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-(2S,3S)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol hydrochloride (175590-75-7) → (E)-(2R)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethyl-amine (809282-31-3) + (Z)-(2R)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethyl-amine (809282-30-2) + (Z)-(2R)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethyl-amine hydrochloride + (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride (197144-97-1)

Guidance literature:

(-)-(2S,3S)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol hydrochloride; With formic acid; for 4h; Heating / reflux;

With sodium hydroxide; In water; ethyl acetate; pH=11; Product distribution / selectivity;

Reference yield:

→ (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride (197144-97-1)

Guidance literature:

Reference yield:

(Z)-(2R)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethyl-amine hydrochloride + (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride (197144-97-1) → (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine (175591-22-7) + (2R,3S)-1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentane

Guidance literature:

(Z)-(2R)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethyl-amine hydrochloride; (E)-(RS)-[3-(3-methoxy-phenyl)-2-methyl-pent-3-enyl]-dimethylamine hydrochloride; With hydrogen; 5%-palladium/activated carbon; In water; at 45 ℃; under 750.075 - 3750.38 Torr;

With sodium hydroxide; In water; Product distribution / selectivity;

upstream raw materials:

(-)-(2S,3S)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol hydrochloride

Downstream raw materials:

(βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine

Refernces

• 1、 -. "Dimethyl-(3-aryl-but-3-enyl)-amine compounds as pharmaceutical active ingredients". . . Retrieved 2008/06/13.